Preschool neurodevelopment in Zika virus-exposed children without congenital Zika syndrome. [PDF]
Children with in utero Zika virus (ZIKV) exposure without congenital Zika syndrome (CZS) are at risk for abnormal neurodevelopment. Preschool-age outcomes for children with antenatal ZIKV exposure have not yet been established.Children with in utero ZIKV exposure and non-exposed controls had neurodevelopmental evaluations at age 3-5 years in ...
Mulkey SB +14 more
europepmc +3 more sources
Congenital Zika syndrome: A systematic review
BackgroundThe signs and symptoms of Zika virus infection are usually mild and self-limited. However, the disease has been linked to neurological complications such as Guillain-Barré syndrome and peripheral nerve involvement, and also to abortion and fetal deaths due to vertical transmission, resulting in various congenital malformations in newborns ...
Danielle A. Freitas +6 more
openaire +6 more sources
In February 2016, the World Health Organization declared Zika virus (ZIKV) infection a public health emergency of international concern because it caused congenital Zika syndrome (CZS). The CZS is considered a specific pattern of birth defects caused by ZIKV infection, which is transmitted by the bite of the Aedes aegypti mosquito.
Israel E. Crisanto-López +3 more
openaire +4 more sources
Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities. [PDF]
During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly shown to cause fetal loss and congenital malformations in acutely and chronically infected pregnant women.
Aagaard, Kjersti M +17 more
core +2 more sources
Blocking Zika virus vertical transmission. [PDF]
The outbreak of the Zika virus (ZIKV) has been associated with increased incidence of congenital malformations. Although recent efforts have focused on vaccine development, treatments for infected individuals are needed urgently. Sofosbuvir (SOF), an FDA-
Beltrão-Braga, Patricia CB +23 more
core +2 more sources
Zika virus infection in the returning traveller: what every neurologist should know [PDF]
Zika virus has been associated with a wide range of neurological complications. Neurologists in areas without current active transmission of the virus may be confronted with Zika-associated neurological disease, as a large number of returning travellers ...
Brito Ferreira, Maria Lucia +6 more
core +6 more sources
Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]
Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas +5 more
core +2 more sources
Neuroimaging Findings in Congenital Zika Syndrome [PDF]
Since the early 2015 outbreak of the Zika virus, an arbovirus originally identified in Africa and Asia-Pacific and transmitted by Aedes aegypti mosquitoes, the virus has spread rapidly from Pernambuco State throughout Brazil and the Americas.
A. Poretti, T.A.G.M. Huisman
openaire +2 more sources
Cost-effectiveness of a potential Zika vaccine candidate: a case study for Colombia [PDF]
Background: A number of Zika vaccine platforms are currently being investigated, some of which have entered clinical trials. We sought to evaluate the cost-effectiveness of a potential Zika vaccine candidate under the WHO Vaccine Target Product Profile ...
Moghadas, Seyed +2 more
core +2 more sources
Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses [PDF]
The recent outbreak of infection with Zika virus (ZIKV; Flaviviridae) has attracted attention to this previously neglected mosquito-borne pathogen and the need for efficient therapies.
Donald, Claire L. +4 more
core +1 more source

