Results 31 to 40 of about 11,985 (168)

The EUROmediCAT Network and Databases: A Resource for Pharmacovigilance in Pregnancy

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Background The evidence gap relating to the risk of congenital anomalies (CA) associated with first trimester medication exposure in pregnancy is well recognized. Aims We describe the EUROmediCAT network and databases, and the methodological approach to pregnancy pharmacovigilance.
Helen Dolk, Christine Damase‐Michel, Joan Morris, Amanda Neville, Ester Garne, Sue Jordan, Anke Rissmann, Alessio Coi, Deirdre Folan, Dieuwke Broekstra, Jennifer M. Broughan, Lea Bruneau, Clara Cavero‐Carbonell, Elly den Hond, Miriam Gatt, Mika Gissler, Babak Khoshnood, Anna Latos Bielenska, Hedvig Nordeng, Ljubica Odak, Mary O'Mahony, Isabelle Perthus, J. Luke Richardson, Florence Rouget, Joanna Sichitiu, David Tucker, Natalya Zymak‐Zakutnya, Maria Loane   +27 more
wiley   +1 more source

Zika fever and congenital Zika syndrome: An unexpected emerging arboviral disease [PDF]

Journal of Infection, 2016
Unlike its mosquito-borne relatives, such as dengue, West Nile, and Japanese encephalitis viruses, which can cause severe human diseases, Zika virus (ZIKV) has emerged from obscurity by its association with a suspected "congenital Zika syndrome", while causing asymptomatic or mild exanthematous febrile infections which are dengue- or rubella-like in ...
Yuen, KY, Cheng, VCC, Yip, CY, CHOI, KY, Chan, JFW   +4 more
openaire   +7 more sources

Congenital microcephaly: Case definition & guidelines for data collection, analysis, and presentation of safety data after maternal immunisation. [PDF]

, 2017
Need for developing case definitions and guidelines for data collection, analysis, and presentation for congenital microcephaly as an adverse event following maternal immunisation Congenital microcephaly, also referred to as primary microcephaly due ...
Abuelo, Alisa Kachikis, Alison Tse Kawai, Angelo, Angelo, Anju Shrestha, Azucena Bardají, Barkovich, Beckie N. Tagbo, Buck Louis, Cauchemez, Clare L. Cutland, Czeizel, de Fatima Vasco Aragao, de Oliveira, de Oliveira-Szejnfeld, de Onis, DeSilva, Dolk, Erick Sell, Fabiani, Flor M. Munoz, Fyezah Jehan, Garland, Goss, Hans Spiegel, Harjulehto-Mervaala, Heikkinen, Helen Marshall, Huang, James M. Oleske, Kallen, Kallen, Keller-Stanislawski, Kohl, Kohl, Kohl, Leal, Linda O. Eckert, Malini DeSilva, McMillan, Mirjana Nesin, Morgan, Moro, Munoz, Nakalembe, Nicola P. Klein, Obican, Opitz, Oppermann, Ouandaogo, Papageorghiou, Papageorghiou, Papageorghiou, Passemard, Pasternak, Paul Heath, Rasmussen, Roche, Russell, Santa Cruz, Shakib, Silveira, Soares de Araújo, Society for Maternal-Fetal Medicine Publications C, Sonali Kochhar, Sukumaran, Ventura, von der Hagen, Wilson, Zheteyeva   +70 more
core   +3 more sources

Ocular Histopathologic Features of Congenital Zika Syndrome [PDF]

JAMA Ophthalmology, 2017
Congenital Zika syndrome (CZS) is known to be associated with severe malformations in newborns. Although microcephaly is the hallmark of this disease, the ocular findings are important given the severe visual impairment that has been observed in these patients. Regardless of the increased number of CZS cases reported, to date, no studies have described
Maria P, Fernandez, Edgar, Parra Saad, Martha, Ospina Martinez, Sheryl, Corchuelo, Marcela, Mercado Reyes, Maria Jose, Herrera, Miguel, Parra Saavedra, Angelica, Rico, Angela M, Fernandez, Richard K, Lee, Camila V, Ventura, Audina M, Berrocal, Sander R, Dubovy   +12 more
openaire   +2 more sources

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

Advanced Intelligent Discovery, Volume 2, Issue 2, April 2026.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki, Bassam Bachour Junior, Marcelo Mulato, José Ilton de Oliveira Filho   +3 more
wiley   +1 more source

Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected [PDF]

, 2017
The recent global outbreak of Zika virus (ZIKV) infection has been linked to severe neurological disorders affecting the peripheral and central nervous systems (PNS and CNS, respectively). The pathobiology underlying these diverse clinical phenotypes are
Barnett, Susan C., Barrie, Jennifer A., Brennan, Benjamin, Cumberworth, Stephanie L., Cunningham, Madeleine E., de Oliveira França, Rafael Freitas, Edgar, Julia M., Gomes de Figueiredo, Daniely Paulino, Kohl, Alain, Linington, Christopher, Pena, Lindomar J., Schultz, Verena, Wilder-Smith, Adrian J., Willison, Hugh J.   +13 more
core   +1 more source

A gorilla adenovirus-based vaccine against Zika virus induces durable immunity and confers protection in pregnancy [PDF]

, 2019
The teratogenic potential of Zika virus (ZIKV) has made the development of an effective vaccine a global health priority. Here, we generate two gorilla adenovirus-based ZIKV vaccines that encode for pre-membrane (prM) and envelope (E) proteins (GAd-Zvp ...
Brough, Douglas E, Curiel, David T, Diamond, Michael S, Dmitriev, Igor P, Fremont, Daved H, Hassan, Ahmed O, Kashentseva, Elena A, Zhao, Haiyan   +7 more
core   +1 more source

Zika Virus Induces Apoptosis in Retinal Pigmented Epithelial Cells [PDF]

, 2020
Zika virus is a single-stranded positive sense RNA virus that attracted international attention in 2015 when an epidemic broke out in Brazil. This vector borne virus is transmitted by mosquitos and is especially concerning for pregnant women because the ...
Kraus, Madison, Muthuraj, Philma Glora, Natarajan, Sathish Kumar   +2 more
core   +1 more source

Infants' General Movements Were Not Affected by Exposure to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 Infections

Acta Paediatrica, Volume 115, Issue 4, Page 913-922, April 2026.
ABSTRACT Aim Prenatal maternal infections may impair infant brain development. This study investigated the effect of maternal infections with the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) during pregnancy on infant neurodevelopment by assessing general movements (GMs).
Kathrin Neumayr, Katharina Lippert, A. Sebastian Schroeder, Vinzenz G. Eck, Uta Tacke, Sevil Üzer, Andreas W. Flemmer, Mathias Klemme, Claudia Nussbaum, Nikolas Hesse, Sergi Pujades, Leander Behr, Sonja Strieker, Florian Heinen, Mirjam N. Landgraf   +14 more
wiley   +1 more source

Expression of Purinergic and Endothelial Activation Markers in Brain Tissue From Fatal Microcephaly Associated With ZIKV

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background Zika virus (ZIKV) is a flavivirus that has gained global attention due to its association with congenital microcephaly and neuroinflammatory responses. Markers of endothelial activation and purinergic signaling have been identified in the context of ZIKV neuropathogenesis, although the underlying mechanisms remain poorly understood.
Jorge Rodrigues de Sousa, Gustavo Batista Ferro, Leticia Vieira Teixeira, Carlos Silva, Ligia Lima, Orlando Neto, Raimunda Azevedo, Jannifer Oliveira Chiang, Livia Medeiros Neves Casseb, Arnaldo Jorge Martins Filho, Lívia Caricio Martins, Juarez Antônio Simões Quaresma, Pedro Fernando da Costa Vasconcelos   +12 more
wiley   +1 more source