Results 101 to 110 of about 197,951 (371)
Advanced Science, EarlyView.PDZK1 down‐regulation couples high‐glucose stress to RPE senescence via a PDZK1–14‐3‐3ε–mTOR axis. Restoring PDZK1 or clearing senescent cells rescues retinal homeostasis and mitigates early diabetic retinopathy (DR). This study provides direct evidence linking RPE cell senescence to DR pathogenesis and reveals a promising therapeutic strategy for DR ...
Jian Zhao +6 more
wiley +1 more source
Frontiers in Physiology, 2018 Type 2 Diabetes mellitus (T2DM) is closely correlated with cognitive impairment and neurodegenerative disease. Bushen Huoxue (BSHX) is a compound Chinese medicine used clinically to treat diabetes-induced cognitive impairment.
Yuan Li +32 more
doaj +1 more source
Microcirculation in the labyrinth [PDF]
Archives of Oto-Rhino-Laryngology, 1976 The inner ear is unique in the number and variety of specialized microvascular networks that furnish blood to its parts. Four distinct capillary networks arranged in parallel supply the structures of the outer wall, and four others those of the spiral lamina.
openaire +4 more sources
Microconfined flow behavior of red blood cells by image analysis techniques [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +4 more
core
Comparison of the new OPS Imaging technique with intravital microscopy: Analysis of the colon microcirculation [PDF]
, 2002 Background. The OPS imaging technique has been introduced for in vivo assessment of microcirculation in humans. The aim of this study was to validate the new technique against intravital fluorescence microscopy (IFM) for the visualization of colon ...
Biberthaler, Peter, Langer, S.
core +1 more source
Advanced Science, EarlyView.The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang +28 more
wiley +1 more source
Physiology and prevention of heel ulcers: The state of science [PDF]
, 2003 The prevalence of heel ulcers across settings is high and is increasing. Prevention of ulcers requires knowledge of their etiology and the scientific basis for preventive care. The interaction between external pressure and the heel vasculature is central
Stotts, N. A, Wong, Vivian K.
core +2 more sources
Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined
Aggregate, EarlyView.Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei +8 more
wiley +1 more source
Investigative Ophthalmology and Visual Science, 2016 Purpose To investigate the vascular microcirculation changes in the retinal nerve fiber layer (RNFL) in normal, glaucoma suspect, and open-angle glaucoma (OAG) groups using optical coherence tomography–based microangiography (OMAG).
Chieh-Li Chen +9 more
semanticscholar +1 more source
Microcirculation in Hypertension [PDF]
, 2003 Increased peripheral vascular resistance is considered the hallmark of hypertension (1). This increased vascular resistance is chiefly determined at the microvascular level, in particular at the small arteries and precapillary arterioles, and it is likely to reflect functional and structural changes of these vessels (2) (Table 1).
AMBROSIO, Giuseppe +2 more
openaire +3 more sources