Results 111 to 120 of about 145,462 (317)

Endothelial β-catenin upregulation and Y142 phosphorylation drive diabetic angiogenesis via upregulating KDR/HDAC9

Cell Communication and Signaling
Background Diabetic angiogenesis is closely associated with disabilities and death caused by diabetic microvascular complications. Advanced glycation end products (AGEs) are abnormally accumulated in diabetic patients and are a key pathogenic factor for ...
Zhenfeng Chen, Bingqi Lin, Xiaodan Yao, Jie Weng, Jinlian Liu, Qi He, Ke Song, Chuyu Zhou, Zirui Zuo, Xiaoxia Huang, Zhuanhua Liu, Qiaobing Huang, Qiulin Xu, Xiaohua Guo   +13 more
doaj   +1 more source

Design of a bioreactor to study the role of red blood cells in the transport of nitric oxide in the microcirculation [PDF]

, 2007
Nitric oxide (NO) plays an important role in physiological functions like vasodilation, neurotransmission, and inhibition of platelet aggregation. The endothelium-derived NO diffuses into the vascular lumen where it interacts with flowing blood as well ...
Bhise, Nupura, Kavdia, Mahendra
core   +2 more sources

Inflammatory response to implantation of transparent nanocrystalline yttria-stabilized zirconia using a dorsal window chamber model. [PDF]

, 2016
The long-range goal of the windows to the brain (WttB) is to improve patient care by providing a technique for delivery and/or collection of light into/from the brain, on demand, over large areas, and on a chronically-recurring basis without the need for
Aguilar, Guillermo, Cabrales, Pedro, Damestani, Yasaman, Galan-Hoffman, Diego E, Ortiz, Daniel   +4 more
core   +1 more source

Synthetic Fourier Domain Optical Coherence Tomography

Advanced Photonics Research
A novel approach for image formation in optical coherence tomography (OCT) and microscopy is presented. The depth resolution of OCT, including recently developed nanosensitive OCT (nsOCT), is limited by the spectral bandwidth of the light source used for
Sergey Alexandrov, Ryan McAuley, Rajib Dey, Anand Arangath, Yi Zhou, Andrew Nolan, Peter Owens, Martin Leahy   +7 more
doaj   +1 more source

Particulate Matter Exposure Impairs Systemic Microvascular Endothelium-Dependent Dilation [PDF]

, 2004
Acute exposure to airborne pollutants, such as solid particulate matter (PM), increases the risk of cardiovascular dysfunction, but the mechanisms by which PM evokes systemic effects remain to be identified.
Barger, Mark, Boegehold, Matthew A., Castranova, Vincent, Nurkiewicz, Timothy R., Porter, Dale W.   +4 more
core   +3 more sources

Research progress of neurovascular units involved in ischemic stroke

Ibrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang, Hao Tong, Zhuo‐Fan Ye, Zu‐Cai Xu, Tao Tao   +4 more
wiley   +1 more source

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

Periodontology 2000, EarlyView., 2023
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti, Jean E. Suvan, Francesco D'Aiuto   +2 more
wiley   +1 more source

Adiponectin improves coronary no-reflow injury by protecting the endothelium in rats with type 2 diabetes mellitus. [PDF]

, 2017
To determine the effect of adiponectin (APN) on the coronary no-reflow (NR) injury in rats with Type 2 diabetes mellitus (T2DM), 80 male Sprague-Dawley rats were fed with a high-sugar-high-fat diet to build a T2DM model.
Han, Xue, Liu, Huirong, Liu, Xin, Lv, Tingting, Ma, Lu, Ma, Xin-Liang, Sun, Qi, Wang, Ke, Wang, Wen, Wu, Ye, Xu, Wenli, Zhang, Suli   +11 more
core   +2 more sources

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka   +11 more
wiley   +1 more source

Effect of Baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis [PDF]

, 2008
Objective: To investigate the effect of Bacailin on inflammatory mediator levels and microcirculation disturbance in severe acute pancreatitis (SAP) rats and explore its therapeutic mechanism on this disease. Methods: SAP model rats were randomly divided
Chen-Jun Wu, Hua Tian, Li Chen, Qi Xie, Qian Ye, Ru-Jun Xu, Wenqin Yuan, Xin-Ge Jiang, Xiping Zhang, Yang Cai   +9 more
core   +1 more source