Results 131 to 140 of about 29,995 (215)

Adjuvant therapy with total salvianolic acid injection enhances the safety and efficacy of recombinant prourokinase in ischemic stroke by mitigating blood–brain barrier disruption

Journal of Translational Medicine
Background Late-phase thrombolysis within the 4.5-hour window for acute ischemic stroke exacerbates blood-brain barrier (BBB) disruption, increasing the risk of hemorrhagic transformation.
Xiao-Yi Wang, Quan Li, Li Yan, Di Wang, Chun-Shui Pan, Jing-Yu Fan, Zhi-Zhong Ma, Jing-Yan Han   +7 more
doaj   +1 more source

Disseminated intravascular coagulation as a prognostic factor in heatstroke: a retrospective cohort study based on Japanese insurance claims

Frontiers in Medicine
PurposeHeatstroke is an emerging global health concern, particularly among the elderly. Disseminated intravascular coagulation (DIC) complicates about 20% of these cases and contributes to poor outcomes.
Hiroyuki Koami, Hiroyuki Koami, Yutaro Furukawa, Yutaro Furukawa, Hiroki Ushijima, Hiroki Ushijima, Daisuke Muroya, Daisuke Muroya, Tadashi Matsuoka, Tadashi Matsuoka, Takaaki Totoki, Takaaki Totoki, Kenji Kandori, Kenji Kandori, Takahiro Oishi, Takahiro Oishi, Kasumi Satoh, Yutaka Umemura, Yutaka Umemura, Kazuma Yamakawa, Kazuma Yamakawa, Mineji Hayakawa, Mineji Hayakawa, Kohji Okamoto, Kohji Okamoto, Yuichiro Sakamoto, Yuichiro Sakamoto   +26 more
doaj   +1 more source

Physiology and Pathophysiology of Microcirculation

, 2015
International audienceMicrocirculation is the vascular compartments corresponding to vessels, the bore of which ranges from about five to a few hundred μm. Microcirculation possesses four main categories of conduits: arterioles, capillaries, venules, and
Thiriet, Marc, Marc Thiriet
core   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source

Blood flow-based platelet aggregation and thrombosis formation on biomimetic microcirculation system

, 2012
Blood flow-based platelet aggregation and thrombosis formation on biomimetic microcirculation ...
张旭朗, 秦建华
core  

Microcirculation-mediated preconditioning and intracellular hypothermia

, 2018
Microcirculation is a network of perfused capillaries that connects macrocirculation with the cells. Although research has provided insight into microcirculatory blood flow, our knowledge remains limited.
Chalkias, A., Xanthos, T., Mamais, I., Chalkias A., Mamais I., Xanthos T.   +3 more
core   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Protein C preserves microcirculation in a model of neonatal septic shock

, 2009
Doris Fischer1, Marcel F Nold2, Claudia A Nold-Petry2, Antonio Furlan2, Alex Veldman31Department of Pediatrics, Hospital of the J W Goethe University, Frankfurt, Germany; 2Division of Infectious Diseases, University of Colorado Denver, Aurora, CO, USA ...
Doris Fischer, Claudia A Nold-Petry, et al, Marcel F Nold   +3 more
core  

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

Small, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan, Bei Song, Chengyun Liu, Peiyu Zhong, Quan Zhou, Xiaofang Zhao, Guangyu Gao, Xinyue Zhang, Xueke Guang, Tianci Yao, Ting Liu, Hao Zhang, Xinqi Diao, Weilin Lu   +13 more
wiley   +1 more source