Results 151 to 160 of about 26,493 (264)

Canal Cholesteatoma Presentation and Management: A Systematic Review and Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate current understanding of external auditory canal cholesteatoma (EACC), its symptomatic burden, clinical features, diagnostic approach, and management strategies to reduce delays in diagnosis. Data Sources PubMed, CINAHL, COCHRANE Library, and SCOPUS.
Angelica M. Walker, Matthew Cheung, Shaun A. Nguyen, Kate Bonham, Erin A. Harvey, Robert F. Labadie, Ted A. Meyer   +6 more
wiley   +1 more source

IL-1β primed mesenchymal stromal cells moderate hemorrhagic shock-induced vascular permeability

Journal of Translational Medicine
Background Hemorrhagic shock (HS) corresponds to absolute hypovolemia creating an imbalance between oxygen supply and consumption. This causes an impaired hemostasis, a systemic inflammatory response, and microvascular permeability which can lead to ...
Nathalie Baudry, Aurélie Campeanu, Clotilde Aussel, Caroline Doutrelon, Marion Grosbot, Sébastien Banzet, Eric Vicaut, Juliette Peltzer   +7 more
doaj   +1 more source

CLEC14A correlates with neutrophil infiltration in hepatocellular carcinoma and mediates neutrophil recruitment across liver endothelial cells

The Journal of Pathology, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke, Dean Kavanagh, Ayla O'Keeffe, Kylie Savoye, Kaiyi Yang, Daniel A Patten, Catherine E Willoughby, Josep M Llovet, Georgiana Neag, Helen L Reeves, Peter W Hewett, Neena Kalia, Tahir Shah, Yuk Ting Ma, Kelly Hunter, Joe Flint, Jack L McMurray, Owen Cain, Fabian Spill, Derek A Mann, Amy J Naylor, Victoria Heath, Christopher J Weston, Roy Bicknell, Shishir Shetty   +24 more
wiley   +1 more source

Microcirculatory changes and its evaluation

This thesis aims to provide an overview of microcirculation, including its anatomy and hemorheological properties. Within the framework of microcirculatory dysfunction, there are 4 main types, and their effects are seen in sepsis and ischemia-reperfusion
Sukhbaatar, Enkhjin
core  

Evaluating the efficacy of obturator cryoneurolysis for hip adductor spasticity: An observational, prospective study

PM&R, EarlyView.
Abstract Background Hip adductor spasticity is a common affliction among patients with disorders of the central nervous system. Cryoneurolysis is a novel intervention for spasticity involving the application of extreme cold to a nerve. This induces axonal breakdown, relieving spasticity.
Fraser MacRae, Mahdis Hashemi, Paul Winston   +2 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Progress On Sensorineural Hearing Loss: Mechanisms and Therapies

Sensory Neuroscience, EarlyView.
ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang, Shen Li, Yangfan Zhou, Duopin Li, Junru Ding, Ruifeng Qiao, Yutian Chen, Fanglei Ye, Le Wang, Peipei Li   +9 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Audiological Characteristics in Vestibular Schwannoma Patients

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Vestibular schwannoma (VS) is a benign tumor that originates from the Schwann cells of the vestibular nerve sheath in the internal auditory canal. This retrospective study collected data from patients with VS who underwent surgical treatment to identify their demographic characteristics and audiometric features.
Shan Zeng, Yi‐Yun Lou, Hui‐Qian Yu, Wei‐Dong Zhao, Wen‐Yan Li   +4 more
wiley   +1 more source

Effect of Baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis

, 2008
Objective: To investigate the effect of Bacailin on inflammatory mediator levels and microcirculation disturbance in severe acute pancreatitis (SAP) rats and explore its therapeutic mechanism on this disease. Methods: SAP model rats were randomly divided
Hua Tian, Qian Ye, Ru-Jun Xu, Xin-Ge Jiang, Li Chen, Yang Cai, Xiping Zhang, Qi Xie, Wenqin Yuan, Chen-Jun Wu   +9 more
core