Results 21 to 30 of about 2,206,281 (240)

Fractional Flow Reserve and Instantaneous Wave‐Free Ratio Predict Pathological Wall Shear Stress in Coronary Arteries: Implications for Understanding the Pathophysiological Impact of Functionally Significant Coronary Stenoses

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background The pathophysiological mechanism behind adverse outcomes associated with ischemia‐inducing epicardial coronary stenoses and microcirculatory dysfunction remains unclear. Wall shear stress (WSS) plays an important role in atherosclerotic plaque
Christopher C. Y. Wong, Ashkan Javadzadegan, Cuneyt Ada, Jerrett K. Lau, Ravinay Bhindi, William F. Fearon, Leonard Kritharides, Martin K. C. Ng, Andy S. C. Yong   +8 more
doaj   +1 more source

Microvascular Dysfunction in Patients With Type II Diabetes Mellitus: Invasive Assessment of Absolute Coronary Blood Flow and Microvascular Resistance Reserve

Frontiers in Cardiovascular Medicine, 2021
Background: Coronary microvascular dysfunction (CMD) is an early feature of diabetic cardiomyopathy, which usually precedes the onset of diastolic and systolic dysfunction.
Emanuele Gallinoro, Emanuele Gallinoro, Pasquale Paolisso, Pasquale Paolisso, Alessandro Candreva, Konstantinos Bermpeis, Davide Fabbricatore, Davide Fabbricatore, Giuseppe Esposito, Giuseppe Esposito, Dario Bertolone, Dario Bertolone, Estefania Fernandez Peregrina, Daniel Munhoz, Daniel Munhoz, Daniel Munhoz, Niya Mileva, Martin Penicka, Jozef Bartunek, Marc Vanderheyden, Eric Wyffels, Jeroen Sonck, Jeroen Sonck, Carlos Collet, Bernard De Bruyne, Bernard De Bruyne, Emanuele Barbato, Emanuele Barbato   +27 more
doaj   +1 more source

Continuous Versus Bolus Thermodilution‐Derived Coronary Flow Reserve and Microvascular Resistance Reserve and Their Association With Angina and Quality of Life in Patients With Angina and Nonobstructive Coronaries: A Head‐to‐Head Comparison

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Coronary flow reserve (CFR) and microvascular resistance reserve (MRR) are physiological parameters to assess coronary microvascular dysfunction. CFR and MRR can be assessed using bolus or continuous thermodilution, and the correlation between
Tijn P. J. Jansen, Annemiek de Vos, Valeria Paradies, Aukelien Dimitriu‐Leen, Caïa Crooijmans, Suzette Elias‐Smale, Laura Rodwell, Angela H. E. M. Maas, Pieter C. Smits, Nico Pijls, Niels van Royen, Peter Damman   +11 more
doaj   +1 more source

Epicardial Stenosis Severity Does Not Affect Minimal Microcirculatory Resistance [PDF]

Circulation, 2004
Background— Whether minimal microvascular resistance of the myocardium is affected by the presence of an epicardial stenosis is controversial. Recently, an index of microcirculatory resistance (IMR) was developed that is based on combined measurements of distal coronary pressure and thermodilution ...
Aarnoudse, W.H., Fearon, W.F., Manoharan, G., Geven, M.C.F., Vosse, van de, F.N., Rutten, M.C.M., Bruyne, de, B., Pijls, N.H.J.   +7 more
openaire   +6 more sources

Investigation of Microcirculatory in Resistive Arteries [PDF]

Biomedical and Medical Science, 2020
Тhe article shows the physiological significance of resistive arteries in relation to blood flow. The article describes a new non-invasive method for assessing the functional state of resistive arteries, which indicates the resistance of resistive arteries.
openaire   +1 more source

Angiography-derived index of microcirculatory resistance as risk stratification tool in dilated cardiomyopathy [PDF]

International Journal of Cardiology. Cardiovascular Risk and Prevention
Ioannis Skalidis, Philippe Garot, Mariama Akodad, Stephane Cook, Panagiotis Antiochos   +4 more
doaj   +2 more sources

Effects of Intracoronary Alteplase on Microvascular Function in Acute Myocardial Infarction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Impaired microcirculatory reperfusion worsens prognosis following acute ST‐segment–elevation myocardial infarction. In the T‐TIME (A Trial of Low‐Dose Adjunctive Alteplase During Primary PCI) trial, microvascular obstruction on cardiovascular ...
Annette M. Maznyczka, Peter J. McCartney, Keith G. Oldroyd, Mitchell Lindsay, Margaret McEntegart, Hany Eteiba, Paul Rocchiccioli, Richard Good, Aadil Shaukat, Keith Robertson, Vivek Kodoth, John P. Greenwood, James M. Cotton, Stuart Hood, Stuart Watkins, Peter W. Macfarlane, Julie Kennedy, R. Campbell Tait, Paul Welsh, Naveed Sattar, Damien Collison, Lynsey Gillespie, Alex McConnachie, Colin Berry   +23 more
doaj   +1 more source

Index of microcirculatory resistance in the assessment of coronary microvascular dysfunction in hypertrophic cardiomyopathy

Revista Portuguesa de Cardiologia, 2022
Coronary microvascular dysfunction (CMD) is one of the most important pathophysiological features in hypertrophic cardiomyopathy (HCM). The index of microcirculatory resistance (IMR) is an invasive method to assess the coronary microcirculation. The aim was to assess CMD in patients with HCM by IMR.Adult patients with HCM without epicardial coronary ...
Aguiar Rosa, S, Mota Carmo, M, Rocha Lopes, L, Oliveira, E, Thomas, B, Baquero, L, Cruz Ferreira, R, Fiarresga, A   +7 more
openaire   +4 more sources

Remote Ischemic Preconditioning Acutely Improves Coronary Microcirculatory Function

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Remote ischemic preconditioning (RIPC) attenuates myocardial damage during elective and primary percutaneous coronary intervention. Recent studies suggest that coronary microcirculatory function is an important determinant of clinical outcome.
Jerrett K. Lau, Probal Roy, Ashkan Javadzadegan, Abouzar Moshfegh, William F. Fearon, Martin Ng, Harry Lowe, David Brieger, Leonard Kritharides, Andy S. Yong   +9 more
doaj   +1 more source

Coronary Microcirculation Downstream Non‐Infarct‐Related Arteries in the Subacute Phase of Myocardial Infarction: Implications for Physiology‐Guided Revascularization

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Concerns exist about reliability of pressure‐wire‐guided coronary revascularization of non‐infarct‐related arteries (non‐IRA). We investigated whether physiological assessment of non‐IRA during the subacute phase of myocardial infarction might
Hernán Mejía‐Rentería, Joo Myung Lee, Nina W. van der Hoeven, Nieves Gonzalo, Pilar Jiménez‐Quevedo, Luis Nombela‐Franco, Iván J. Núñez‐Gil, Pablo Salinas, María Del Trigo, Enrico Cerrato, Niels van Royen, Paul Knaapen, Bon‐Kwon Koo, Carlos Macaya, Antonio Fernández‐Ortiz, Javier Escaned   +15 more
doaj   +1 more source