Results 51 to 60 of about 7,537 (304)

Making Microcomputers Accessible to Blind Persons

open access: yes, 1986
Without specialized “access technology,” blind students are precluded from full access to microcomputers. Research on multimedia access to microcomputers has explored tactile, auditory, and visual means of access.
Michael F. Young   +2 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Problems of Using Computers in Accounting Education and Profession in Developing Countries: Case of IRAN [PDF]

open access: yesبررسی‌های حسابداری و حسابرسی, 1995
Imported technology has always had special problems in developing countries Withitself . In accounting field, one new problem is appeared too: "unbalanced Growth (Development) of accounting and computers".This problem , although has had some of its ...
دکتر محمد عرب مازاد یزدی
doaj  

Computers in the writing processadvantage or disadvantage?

open access: yesPer Linguam : A Journal of Language Learning, 2013
This paper tries to find an answer to the question of whether the microcomputer could be put to meaningful .Jse in the teaching of writing techniques to students.
Jannie Botha
doaj   +1 more source

PlasPI marine cameras: Open-source, affordable camera systems for time series marine studies

open access: yesHardwareX, 2020
Imaging underwater can be particularly problematic and expensive given the harsh environmental conditions posed by salinity and for some deployments, pressure. To counter these difficulties, expensive waterproof pressure resistant housings are often used,
Autun Purser   +9 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

A Modified Conjugate Gradient Method for the Solution of Sparse Linear Systems on Microcomputers

open access: yes, 1984
A Modified Conjugate Gradient scheme to solve sparse linear systems with positive definite coefficient matrices has been implemented on a microcomputer.
SARTORETTO, Flavio, F. Sartoretto
core  

Do mainframe à nuvem: inovações, estrutura industrial e modelos de negócios nas tecnologias da informação e da comunicação Innovación, estructura industrial y modelos de negocios en las tecnologías de la información y de la comunicación: de los mainframes a la nube From mainframes to the cloud: innovation, industrial structure, and business models in the information and communication technology industry

open access: yesRAUSP: Revista de Administração da Universidade de São Paulo, 2013
Inovações radicais nas tecnologias da informação e da comunicação (TIC) abrem oportunidades para o desenvolvimento de novos modelos de negócios que, quando bem-sucedidos, acabam por alterar a própria estrutura da indústria global.
Paulo Bastos Tigre, Vitor Branco Noronha
doaj  

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