Results 51 to 60 of about 34,632 (278)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

A SURVEY OF MICROCOMPUTER OWNERSHIP AND USAGE

open access: yesPrometheus, 1985
In this paper we present the results of a survey designed to collect information on the use of microcomputers and attitudes towards them. The survey was conducted by mail in the north-eastern part of New South Wales and based on a mailing list used by ...
P. H. Hall   +2 more
doaj   +1 more source

Parallel GPF solution: A GPU‐CPU‐based vectorization parallelization and sparse technique for NR implementation

open access: yesIET Renewable Power Generation, 2021
As an essential simulation tool, global power flow (GPF) can approximately model mutual impacts of interactions between transmission system (TS) and distribution system (DS).
Jingbo Zhao, Yan Tao
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

3-Dimensional simulation of multistage depressed collectors on microcomputers. [PDF]

open access: yes, 1995
A three-dimensional (3-D) package for simulation of asymmetric and crossed-field multistage depressed collectors for microwave tubes has been developed. This package is based upon the 3-D finite-difference code KOBRA3-INP.
Carter, Richard G.   +3 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Problems of Using Computers in Accounting Education and Profession in Developing Countries: Case of IRAN [PDF]

open access: yesبررسی‌های حسابداری و حسابرسی, 1995
Imported technology has always had special problems in developing countries Withitself . In accounting field, one new problem is appeared too: "unbalanced Growth (Development) of accounting and computers".This problem , although has had some of its ...
دکتر محمد عرب مازاد یزدی
doaj  

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