Results 81 to 90 of about 23,887 (275)

Effects of microcystin-LR in isolated perfused rat kidney

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Microcystin is a hepatotoxic peptide which inhibits protein phosphatase types 1 and 2A. The objective of the present study was to evaluate the physiopathologic effects of microcystin-LR in isolated perfused rat kidney.
A.C.L. Nobre   +4 more
doaj   +1 more source

P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders

open access: yesMedicine Bulletin, Volume 1, Issue 2, Page 121-135, December 2025.
ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley   +1 more source

An overview of the toxic effect of potential human carcinogen Microcystin-LR on testis

open access: yesToxicology Reports, 2015
The worldwide occurrence of cyanobacterial blooms due to water eutrophication evokes extreme concerns. These blooms produce cyanotoxins which are hazardous to living organisms.
Yaqoob Lone   +2 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

Evidence for a novel marine harmful algal bloom: cyanotoxin (microcystin) transfer from land to sea otters.

open access: yesPLoS ONE, 2010
"Super-blooms" of cyanobacteria that produce potent and environmentally persistent biotoxins (microcystins) are an emerging global health issue in freshwater habitats.
Melissa A Miller   +14 more
doaj   +1 more source

Multi-Year Assessment of Toxic Genotypes and Microcystin Concentration in Northern Lake Taihu, China

open access: yesToxins, 2016
Lake Taihu is the third-largest freshwater lake in China and has been suffering from cyanobacterial blooms for over two decades. The northern part of the lake, Meiliang Bay, is known to be at high risk of dense and sustained Microcystis blooms and toxins.
Lili Hu   +6 more
semanticscholar   +1 more source

Influence of temperature, mixing, and addition of microcystin‐LR on microcystin gene expression in Microcystis aeruginosa

open access: yesMicrobiologyOpen, 2016
Cyanobacteria, such as the toxin producer Microcystis aeruginosa, are predicted to be favored by global warming both directly, through elevated water temperatures, and indirectly, through factors such as prolonged stratification of waterbodies.
Pia I Scherer   +3 more
semanticscholar   +1 more source

Microcystin-LR Induced Immunotoxicity in Mammals

open access: yesJournal of Toxicology, 2016
Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Exposure to microcystins is a global health problem because of its association with various other pathological effects and people all over the world are ...
Yaqoob Lone, M. Bhide, R. Koiri
semanticscholar   +1 more source

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