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Purification of microcystins

Journal of Chromatography A, 2001
Microcystins are an increasingly important group of bioactive compounds produced by a number of mainly planktonic cyanobacteria. They are a family of cyclic heptapeptides that cause both acute and chronic toxicity. Purified microcystins are utilised in a range of research applications including toxicological and biochemical studies, development of ...
L A, Lawton, C, Edwards
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Effects of microcystins on fish

Environmental Toxicology and Chemistry, 2006
Abstract Microcystins (MCs) are hepatotoxic heptapeptides released into water during or on senescence of cyanobacterial blooms. This review details the different effects of the MCs on fish and discusses their potential consequences in aquatic food webs.
Malbrouck, Christelle   +1 more
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Toxicology and Evaluation of Microcystins

Therapeutic Drug Monitoring, 2000
This paper reviews the toxicity and tumor-promoting properties of microcystins. Methods for screening and/or identification of microcystins in environmental samples are discussed and compared. Specific emphasis is placed on newly developed extraction/detection methods, e.g., solid phase microextraction (SPME) technique, and capillary electrophoresis ...
P K, Lam, M, Yang, M H, Lam
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Microbial Degradation of Microcystins

Chemical Research in Toxicology, 2013
Hepatotoxic microcystins that are produced by freshwater cyanobacteria pose a risk to public health. These compounds may be eliminated by enzymatic degradation. Here, we review the enzymatic pathways for the degradation of these hepatotoxins, some of which are newly discovered processes.
Dariusz, Dziga   +4 more
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Microcystin-LR and chemically degraded microcystin-LR electrochemical oxidation

The Analyst, 2012
Microcystins (MCs) are cyclic hepatotoxic heptapeptides produced by certain strains of freshwater cyanobacteria toxic for humans and animals. The electrochemical behaviour of microcystin-LR (MC-LR) at a glassy carbon electrode (GCE) was investigated using cyclic voltammetry (CV), square wave voltammetry (SWV) and differential pulse voltammetry (DPV ...
Ilanna C, Lopes   +6 more
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the toxicology of microcystins

Toxicon, 1998
Microcystins are a family of more than 50 structurally similar hepatotoxins produced by species of freshwater cyanobacteria, primarily Microcystis aeruginosa. They are monocyclic heptapeptides, characterised by some invariant amino acids, including one of unusual structure which is essential for expression of toxicity.
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Distribution of Microcystin-Producing and Non-Microcystin-Producing Microcystis sp. in European Freshwater Bodies: Detection of Microcystins and Microcystin Genes in Individual Colonies

Systematic and Applied Microbiology, 2004
Microcystis is a well-known cyanobacterial genus frequently producing hepatotoxins named microcystins. Toxin production is encoded by microcystin genes (mcy). This study aims (i) to relate the mcy occurrence in individual colonies to the presence of microcystin, (ii) to assess whether morphological characteristics (morphospecies) are related to the ...
Lorena, Via-Ordorika   +7 more
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Methods for determining microcystins (peptide hepatotoxins) and microcystin-producing cyanobacteria

Water Research, 2006
Episodes of cyanobacterial toxic blooms and fatalities to animals and humans due to cyanobacterial toxins (CBT) are known worldwide. The hepatotoxins and neurotoxins (cyanotoxins) produced by bloom-forming cyanobacteria have been the cause of human and animal health hazards and even death.
Lalita N, Sangolkar   +2 more
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