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Screening for Neurotoxicity with Microelectrode Array

Current Protocols in Toxicology, 2018
Abstract Neurotoxicity and seizurogenic liabilities are difficult to detect using currently available in vitro cytotoxicity assays. This is primarily due to the inherent limitations of these assays to predict adverse neural network disruptions and chemically induced ...
Jenifer A, Bradley   +1 more
openaire   +2 more sources

Towards multifunctional microelectrode arrays

The Analyst, 2008
A single microelectrode array platform, divided into groups of microelectrodes with flexible multiplexing can enable a 'defective' cluster of microelectrodes to be readily identified, by comparing normalised currents with the numbers of microelectrodes in the groups of arrays.
Francisco A, Aguiar   +3 more
openaire   +2 more sources

Array of individually addressable microelectrodes

Sensors and Actuators B: Chemical, 1994
Note: 111 Reference SAMLAB-ARTICLE-1994-006 Record created on 2009-05-12, modified on 2016-08 ...
Fiaccabrino, G. C.   +4 more
openaire   +2 more sources

Arrays of microelectrodes: technologies for environmental investigations

Environmental Science: Processes & Impacts, 2013
Within this work it is our intention to provide an overview of the use of arrays or microelectrodes in the characterisation of environmental samples. Electrochemical methods are often a relatively simple and inexpensive alternative to spectroscopic or chromatographic methods for the analysis of a wide range of analytes.
Frank, Davis, Séamus P J, Higson
openaire   +2 more sources

An Addressable Microelectrode Array for Electrochemical Detection

Analytical Chemistry, 2008
Column and row electrodes on two different glass substrates were orthogonally arranged in order to assemble an addressable microelectrode device for the purpose of comprehensive electrochemical detection. Amperometric signal at the individual crossing point of the column and row electrodes was detected separately on the basis of redox cycling of ...
Zhenyu, Lin   +5 more
openaire   +2 more sources

Flexible microelectrode array for retinal prosthesis

2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2017
fMEA (flexible microelectrode array) is one of the key implantable components for neural stimulating and recording. For its specific implanted environment, it should be designed and fabricated to meet following requirements such as biocompatibility, high-resolution, flexible and low impedance to ensure safety and long-term effective stimulation.
Bin Sun 0011   +5 more
openaire   +2 more sources

An Independent, Temperature-Controllable Microelectrode Array

Analytical Chemistry, 2004
Rapid, localized temperature control and negligible power consumption are key requisites for realizing effective parallel and sequential processing in the miniaturized, integrated biomedical microdevices where temperature-dependent biochemical reactions and fluid flow occur.
Haesik, Yang   +4 more
openaire   +2 more sources

Easy‐to‐Fabricate Conducting Polymer Microelectrode Arrays

Advanced Materials, 2013
A simple and versatile fabrication process is used to define conducting polymer microelectrode arrays (MEAs), patterning at the same time the recording electrodes as well as the insulating layer. Thanks to the low impedance of poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) electrodes, these MEAs allow in vitro recording of action ...
Sessolo, Michele   +7 more
openaire   +3 more sources

Mass Transfer to Microelectrodes and Arrays

Zeitschrift für Physikalische Chemie, 2010
Abstract The properties and advantages of microelectrodes and arrays are reviewed and mass transfer to these microstructures detailed. Various methods for the solution of the mass transfer equations are described, and an overview of analytical and numerical techniques mentioned, including discrete methods, methods of weighted residuals ...
C. A. C. Sequeira, D. M. F. Santos
openaire   +1 more source

Easy-to-Prepare Assembly Array of Tungsten Microelectrodes

IEEE Transactions on Biomedical Engineering, 2005
This paper provides a detailed process flow for fabricating an easy-to-prepare, inexpensive, dense array of tungsten microelectrodes. We designed the process flow to minimize routine tasks by separating an initial preparation of a master mold from a routine preparation of substrate replication, array assembly and tip processing.
Hirokazu Takahashi   +4 more
openaire   +2 more sources

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