Results 131 to 140 of about 45,185 (238)

Rethinking Matrigel: The Complex Journey to Matrix Alternatives in Organoid Culture

open access: yesAdvanced Science, EarlyView.
Matrigel remains the most widely used scaffold in organoid and 3D culture despite its murine origin, variability, and translational limitations. This review discusses the barriers to replacing Matrigel with xeno‐free alternatives and introduces practical tools, including a matrix selection checklist and scaffold assessment criteria, to guide the ...
Lisa Wolff, Sven Hendrix
wiley   +1 more source

Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways

open access: yesAdvanced Science, EarlyView.
Decoding sound from neural activity in mice reveals a striking shift in how the brain encodes sound: from precise but redundant timing codes in early auditory areas to efficient, synergistic rate‐based codes in the cortex. This transformation highlights a robust neural strategy for turning complex acoustic input into coherent perception across the ...
Alexa Buck   +7 more
wiley   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

Fabrication of Sensitive Voltammetric Sensors and Microsensors for Piroxicam by Modifying Nafion and MWCNTs Composite Film on the Electrode Surface

open access: yesElectrochemistry
Piroxicam is a common painkiller and anti-inflammatory drug. Precise monitoring of piroxicam levels can mitigate side effects, but current methods are often slow and complicated. An easily fabricated and highly sensitive voltammetric sensor for piroxicam
Jin LI   +9 more
doaj   +1 more source

Construction and Implementation of Carbon Fiber Microelectrode Arrays for Chronic and Acute <em>In Vivo</em> Recordings [PDF]

open access: bronze, 2021
Kristen Reikersdorfer   +5 more
openalex   +1 more source

Advanced Stem Cell Therapy: 3D‐Bioprinted Brain‐Like Transplants for Alzheimer's Disease‐Like Dementia

open access: yesAdvanced Science, EarlyView.
A tri‐component biomimetic bioink(gelatin/alginate/fibrinogen) is developed to protect cells in critical pathological environments in AD. Using this bioink, a 3D‐printed NPC construct optimized for hippocampal transplantation is provided to improve cell retention and differentiation in an AD‐like model. This approach enhances memory recovery and offers
Ke Gai   +12 more
wiley   +1 more source

Spatially Resolved Mapping of Voltage‐Gated Proton Channel Activity Reveals Delayed Proton Transport in Local Microenvironments

open access: yesAdvanced Science, EarlyView.
A revolutionary imaging platform integrating quantitative single‐molecule photobleaching with ratiometric fluorescence probes enables high‐throughput (≈2300 individually resolvable channels) mapping of individual proton channels in a large field (≈3000 µm2), overcoming the spatial and temporal limitations of conventional electrophysiology.
Jiahua Zhuang   +5 more
wiley   +1 more source

Tuning Microelectrodes’ Impedance to Improve Fast Ripples Recording

open access: yesBioengineering
Epilepsy is a chronic neurological disorder characterized by recurrent seizures resulting from abnormal neuronal hyperexcitability. In the case of pharmacoresistant epilepsy requiring resection surgery, the identification of the Epileptogenic Zone (EZ ...
Hajar Mousavi   +6 more
doaj   +1 more source

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