Results 191 to 200 of about 43,555 (289)

Müller Glia–Vasculature Interactions in the Developing Retina

open access: yesGlia, Volume 74, Issue 10, October 2026.
Retinal vascular layers form normally despite loss of cholinergic retinal waves. Müller glial processes contact endothelial tip cells early and form Aquaporin‐4‐enriched endfeet. Glial endfoot calcium signals are compartmentalized and occur largely independently of neural activity. ABSTRACT Coordinated signaling among neurons, glia, and the vasculature
Samira Monshietehadi   +6 more
wiley   +1 more source

Annexin V‐Functionalized Injectable Calcium‐Deficient Hydroxyapatite for Extracellular Vesicles Binding and Controlled Release

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 10, October 2026.
ABSTRACT Calcium phosphates alone have a limited induction potential in challenging bone conditions, necessitating strategies that enhance cellular responses and matrix‐related processes. An injectable formulation combining calcium‐deficient hydroxyapatite (CDHA) with mesenchymal stem cell‐derived extracellular vesicles may present a promising approach
Eda Ciftci   +5 more
wiley   +1 more source

A Machine Learning Approach That Measures Extracellular pH Within an In Vivo Tumor Model Using acidoCEST MRI

open access: yesNMR in Biomedicine, Volume 39, Issue 10, October 2026.
Machine learning models, particularly RFR (random forest regression), provide accurate and computationally efficient tumor pHe estimation from acidoCEST MRI without requiring auxiliary parametric maps. RFR achieved comparable performance to traditional Bloch fitting (RMSE: 0.020 vs.
Alia Khaled   +6 more
wiley   +1 more source

Multifunctional Composite Coating-Enhanced Flexible Microelectrodes for Chronic, High-Fidelity Neural Signal Recording. [PDF]

open access: yesAnal Chem
Pang J   +11 more
europepmc   +1 more source

Implementation of the In Vitro Seizure Liability Assay (iLAseizure) in Drug Discovery and Development: Mechanism of Action Case Studies

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Central nervous system (CNS) liabilities remain a significant cause of attrition during small molecule drug development. We previously developed the in vitro seizure liability assay (iLAseizure), a new approach methodology (NAM) comprising a human induced pluripotent stem cell neuron microelectrode array (MEA) assay coupled with a panel of ...
Kimberly Rockley   +5 more
wiley   +1 more source

Correction: Multi-sized microelectrode array coupled with micro-electroporation for effective recording of intracellular action potential. [PDF]

open access: yesMicrosyst Nanoeng
Xu X   +12 more
europepmc   +1 more source

An Acidic Tubulointerstitial Microenvironment Delays Cell‐Cycle Progression in Proximal Tubule Cells and Fibroblasts and Synergizes With Lactate to Drive Phenotypic Alterations

open access: yesActa Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Background Chronic kidney disease (CKD) is characterized by progressive tubulointerstitial inflammation and fibrosis, particularly affecting the proximal tubule. Both proximal tubular epithelial cells and interstitial fibroblasts contribute to CKD progression through cell‐cycle arrest and phenotypic transitions.
Marie‐Christin Schulz   +8 more
wiley   +1 more source

Transparent Transfer-Free Ultrasmall Multilayer Graphene Microelectrodes Enable High Quality Recordings in Brain Slices. [PDF]

open access: yesAdv Sci (Weinh)
de Alvarez de Eulate N   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy