Results 1 to 10 of about 12,020 (190)

The Diversity of Fibrillin Functions: Lessons from the Periodontal Ligament [PDF]

open access: yesCells
Marfan syndrome is caused by a mutation in the FBN1 gene encoding fibrillin-1. This extracellular matrix glycoprotein, which assembles into microfibrils, is best known for its scaffolding role in the production of elastic fibers responsible for ...
Elisabeth Genot   +4 more
doaj   +2 more sources

The Biomechanics of Fibrillin Microfibrils: Lessons from the Ciliary Zonule [PDF]

open access: yesCells
Marfan syndrome is an inherited connective tissue disorder that affects the cardiovascular, musculoskeletal, and ocular systems. It is caused by pathogenic variants in the fibrillin-1 gene (FBN1).
Pooja Rathaur   +6 more
doaj   +2 more sources

The Supramolecular Organization of Fibrillin-Rich Microfibrils [PDF]

open access: bronzeThe Journal of Cell Biology, 2001
We propose a new model for the alignment of fibrillin molecules within fibrillin microfibrils. Automated electron tomography was used to generate three-dimensional microfibril reconstructions to 18.6-Å resolution, which revealed many new organizational details of untensioned microfibrils, including heart-shaped beads from which two arms emerge, and ...
Clair Baldock   +7 more
openalex   +6 more sources

Hyaluronate (?) microfibrils in human dermis

open access: hybridActa Dermato-Venereologica, 1971
No abstract ...
T. Kobayasi   +2 more
openalex   +4 more sources

Simulation of Adhesive Contact of Soft Microfibrils [PDF]

open access: yesLubricants, 2020
Adhesive contact between a flat brush structure with deformable microfibrils and an elastic half space is numerically simulated. The stiffness of pillars is modeled by linear springs.
Xin He, Qiang Li, Valentin L. Popov
doaj   +3 more sources

The Shape of Native Plant Cellulose Microfibrils [PDF]

open access: yesScientific Reports, 2018
Determining the shape of plant cellulose microfibrils is critical for understanding plant cell wall molecular architecture and conversion of cellulose into biofuels.
James D. Kubicki   +5 more
doaj   +5 more sources

Extracellular microfibrils in development and disease

open access: greenCellular and Molecular Life Sciences, 2007
Fibrillins are the structural components of extracellular microfibrils that impart physical properties to tissues, alone or together with elastin as elastic fibers. Genetic studies in mice have revealed that fibrillin-rich microfibrils are also involved in regulating developmental programs and homeostatic processes through the modulation of TGF-beta ...
Francesco Ramirez   +3 more
openalex   +5 more sources

Macromolecular crowding enhances fibrillin-1 deposition in the extracellular matrix [PDF]

open access: yesEuropean Cells & Materials, 2022
Biochemical and biophysical factors need consideration when modelling in vivo cellular behaviour using in vitro cell culture systems. One underappreciated factor is the high concentration of macromolecules present in vivo, which is typically not ...
B Satz-Jacobowitz   +3 more
doaj   +1 more source

Electric field bridging-effect in electrified microfibrils’ scaffolds

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Introduction: The use of biocompatible scaffolds combined with the implantation of neural stem cells, is increasingly being investigated to promote the regeneration of damaged neural tissue, for instance, after a Spinal Cord Injury (SCI).
Sara Fontana   +17 more
doaj   +1 more source

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