Results 11 to 20 of about 14,159 (242)
Fibrillin microfibrils are widely distributed extracellular matrix assemblies that endow elastic and nonelastic connective tissues with long-range elasticity. They direct tropoelastin deposition during elastic fibrillogenesis and form an outer mantle for
Cay M. Kielty +7 more
core +5 more sources
The supramolecular organization of fibrillin-rich microfibrils [PDF]
We propose a new model for the alignment of fibrillin molecules within fibrillin microfibrils. Automated electron tomography was used to generate three-dimensional microfibril reconstructions to 18.6-A resolution, which revealed many new organizational ...
Ulrike Ziese +15 more
core +6 more sources
This investigation deals with the detailed procedure for the extraction of microfibrils from raw bamboo. The microfibrils obtained from raw bamboo were characterized using scanning electron microscope and the average diameter of the fibrils was found to
Mikael Skrifvars +5 more
core +3 more sources
The supramolecular organization of collagen VI microfibrils
Collagen VI has a ubiquitous distribution throughout connective tissues, and has key roles in linking cells and matrix macromolecules. We have generated three-dimensional reconstructions of collagen VI microfibrils using automated electron tomography ...
Kielty, Cay M. +3 more
core +3 more sources
The distribution of microfibrils was studied immunohistochemically in intervertebral discs taken from young normal human surgical cases and from the bovine tail.
Jeremy Fairbank +2 more
exaly +2 more sources
Macromolecular crowding enhances fibrillin-1 deposition in the extracellular matrix [PDF]
Biochemical and biophysical factors need consideration when modelling in vivo cellular behaviour using in vitro cell culture systems. One underappreciated factor is the high concentration of macromolecules present in vivo, which is typically not ...
B Satz-Jacobowitz +3 more
doaj +1 more source
Collagen VI microfibril structure reveals mechanism for molecular assembly and clustering of inherited pathogenic mutations [PDF]
Collagen VI links the cell surface to the extracellular matrix to provide mechanical strength to most mammalian tissues, and is linked to human diseases including muscular dystrophy, fibrosis, cardiovascular disease and osteoarthritis.
Alan R. F. Godwin +5 more
doaj +2 more sources
Proteomic analysis of fibrillin-rich microfibrils
MS has been used to investigate the composition of fibrillin-rich microfibrils from non-elastic and elastic tissues, and to compare fibrillin-1 tryptic fingerprints derived from whole zonules, microfibrils and recombinant fibrillin-1.
Kielty, Cay M. +5 more
core +3 more sources
Nanomechanics of collagen microfibrils [PDF]
Collagen constitutes one third of the human proteome, providing mechanical stability, elasticity and strength to organisms and is thus the prime construction material in biology. Collagen is also the dominating material in the extracellular matrix where its stiffness controls cell differentiation, growth and pathology.
VESENTINI, SIMONE +2 more
openaire +4 more sources
Corneal stroma microfibrils [PDF]
Elastic tissue was first described well over a hundred years ago and has since been identified in nearly every part of the body. In this review, we examine elastic tissue in the corneal stroma with some mention of other ocular structures which have been more thoroughly described in the past.
Hanlon, Samuel D. +3 more
openaire +3 more sources

