Results 131 to 140 of about 5,523,474 (277)

Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway.

Proceedings of the National Academy of Sciences of the United States of America, 1999
ERM (Ezrin-Radixin-Moesin) proteins function as plasma membrane-actin cytoskeleton linkers and participate in the formation of specialized domains of the plasma membrane. We have investigated ezrin function in tubulogenesis of a kidney-derived epithelial
Alexis Gautreau, Patrick Poullet, Daniel Louvard, M. Arpin   +3 more
semanticscholar   +1 more source

M2 Macrophage‐Derived Extracellular Vehicles‐Loaded Hyaluronic Acid‐Alginate Hydrogel for Treatment of Osteoarthritis

Orthopaedic Surgery, EarlyView.
ABSTRACT Objective Osteoarthritis (OA), a high‐prevalence degenerative cartilage disease, urgently requires novel therapeutic strategies. M2 macrophage‐derived exosomes (M2‐Exo) demonstrate therapeutic potential for OA, though their regulatory mechanisms in chondrocyte‐macrophage (Mφ) interactions remain to be elucidated.
Wen Zhang, Menghan Luo, Yi Xing, Min Wang, Wenqi Dong, Yuran Su, Xun Sun, Xinlong Ma, Qiang Yang, Yanmei Zhao, Yanhong Zhao   +10 more
wiley   +1 more source

El citoesqueleto de actina: una perspectiva desde la biología molecular del cáncer

Revista Cubana de Investigaciones Biomédicas, 2002
Se realizó una síntesis de los temas que emergen en la actualidad sobre la estructura y organización del citoesqueleto de actina y las vías de señalización que participan en su regulación.
Otmara Guirado Blanco, Montserrat Solanas García, Irmgard Costa Traschel, Eduard Escrich Escriche   +3 more
doaj  

Altered lipid homeostasis in Sertoli cells stressed by mild hyperthermia.

PLoS ONE, 2014
Spermatogenesis is known to be vulnerable to temperature. Exposures of rat testis to moderate hyperthermia result in loss of germ cells with survival of Sertoli cells (SC). Because SC provide structural and metabolic support to germ cells, our aim was to
Ana S Vallés, Marta I Aveldaño, Natalia E Furland   +2 more
doaj   +1 more source

Reversal of aging-induced increases in aortic stiffness by targeting cytoskeletal protein-protein interfaces [PDF]

, 2018
BACKGROUND: The proximal aorta normally functions as a critical shock absorber that protects small downstream vessels from damage by pressure and flow pulsatility generated by the heart during systole.
Chiu, Joanna, Gao, Yuan, Leavis, Paul, Li, Qian, Mitchell, G. F., Morgan, Kathleen, Nicholson, Christopher, Porter, Tyrone, Saphirstein, Robert, Singh, Kuldeep, Verwoert, Germaine   +10 more
core   +1 more source

Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures

Journal of Cell Biology, 1980
A 68,000 mol wt polypeptide has been identified as one of the few major proteins in the microfilament bundles of the microvilli present on intestinal epithelial cells.
A. Bretscher, K. Weber
semanticscholar   +1 more source

The IQ67‐domain protein IQD1 regulates fruit shape through complex multiprotein interactions in pepper (Capsicum annuum L.)

Plant Biotechnology Journal, EarlyView.
Summary Natural genetic variation can be used to improve important crop agronomic traits, and understanding the genetic basis of natural variation in fruit shape can help breeders develop pepper varieties that meet market demand. In this study, we identified a QTL controlling fruit length–width ratio by conventional genetic mapping, encoding a ...
Lianzhen Mao, Yiyu Shen, Qingzhi Cui, Yu Huang, Xiang Zhang, Junheng Lv, Wujun Xing, Dan Zhang, Naying Fang, Daqing Chen, Zhuoxuan Wu, Peiru Li, Minghua Deng, Lijun Ou, Xuexiao Zou, Zhoubin Liu   +15 more
wiley   +1 more source

Desmosomal Molecules In and Out of Adhering Junctions: Normal and Diseased States of Epidermal, Cardiac and Mesenchymally Derived Cells

Dermatology Research and Practice, 2010
Current cell biology textbooks mention only two kinds of cell-to-cell adhering junctions coated with the cytoplasmic plaques: the desmosomes (maculae adhaerentes), anchoring intermediate-sized filaments (IFs), and the actin microfilament-anchoring ...
Sebastian Pieperhoff, Mareike Barth, Steffen Rickelt, Werner W. Franke   +3 more
doaj   +1 more source

Impact of Marine Drugs on Cytoskeleton-Mediated Reproductive Events [PDF]

, 2010
Marine organisms represent an important source of novel bioactive compounds, often showing unique modes of action. Such drugs may be useful tools to study complex processes such as reproduction; which is characterized by many crucial steps that start at ...
Alberti, Alexandre, Allingham, Amador, Ayscough, Azamar, Bai, Bai, Balasubramanian, Barbier, Bates, Beach, Bhakuni, Block, Blunt, Bobinnec, Boni, Botana, Breitbart, Brokaw, Brokaw, Bubb, Bubb, Bubb, Buttino, Calarco, Caldwell, Caldwell, Caldwell, Camatini, Cavas, Chae, Cheng, Cheng, Chiba, Collins, Colman, Connors, Coue, Cruz-Monserrate, Cui, Cuomo, Cuomo, Didry, Diez, d’Ippolito, Ebensperger, Elder, Elisabetta Tosti, Eriksson, Espina, Fenteany, Fischel, Flaherty, Francesco Silvestre, Freile-Pelegrin, Fusetani, Garbers, Gard, Gard, Gard, Gavin, Gennerich, Gennerich, Gibbons, Giganti, Glotzer, Gohla, Grace, Grudzinskas, Grudzinskas, Gunsalus, Gunst, Guttman, Haefner, Hall, Hansen, Hansen, Hart, Hartwell, Heideker, Hertzog, Hirokawa, Hodgson, Hori, Howard, Ianora, Ishihara, Ishijima, James, Jegou, Johnson, Jordan, Kamal, Kim, Kim, Kim, King, Kitagawa, Kloc, Kobayashi, Kobayashi, Kueh, Kumakiri, Kyozuka, Le Guen, Lee, Lim, Lin, Liu, Loisel, Louzao, Lutz, Mabuchi, Mallik, Margolis, Margolis, Maro, Maro, Mayer, McAvey, McDougall, McHardy, Mehlmann, Miller, Miralto, Misamore, Mitchison, Miyazaki, Miyazaki, Mohri, Mohri, Monroy, Moreno-Fierros, Morton, Morton, Mountain, Mozzachiodi, Murray, Murthy, Noguchi, Noguchi, Nusco, Ofuji, Ofuji, Ohizumi, Ohta, Olson, O’Brien, O’Brien, Paul, Paul, Pesando, Pesando, Pettit, Picard, Pielak, Pondaven, Poulet, Prodon, Puppo, Rangel, Reck-Peterson, Redenbach, Redenbach, Rehmann, Rime, Rime, Roegiers, Ryabova, Saito, Saito, Saito, Sanchez-Gutierrez, Sanders, Sardet, Sardet, Sasseville, Satake, Satoh, Schatten, Schatten, Schatten, Schatten, Semenova, Silverman-Gavrila, Silvestre, Silvestre, Simon-Levert, Simon-Levert, Singh, Smith, Smyrniotopoulos, Somma, Spector, Spector, Spector, Speksnijder, Speksnijder, Stein, Stratmhann, Su, Summers, Sun, Sun, Sutovsky, Swain, Takayama, Talbot, Taniyama, Terada, Terada, Terasaki, Theriot, Tilney, Tilney, Toba, Tosti, Tosti, Tosti, Tosti, Usami, Vale, Vale, Vallee, Van Blerkom, Vartiainen, Velichkova, Verlhac, Vilarino, Volmer, Voronina, Wade, Wang, Wang, Weber, Wegner, Wessel, White, Wilson, Xiao, Xu, Yagi, Yamashita, Yan, Yanagimachi, Yang, Yarmola, Yasumoto, Zhong, Zigmond   +250 more
core   +3 more sources

Deformability of Human Mesenchymal Stem Cells Is Dependent on Vimentin Intermediate Filaments [PDF]

, 2017
Mesenchymal stem cells (MSCs) are being studied extensively due to their potential as a therapeutic cell source for many load-bearing tissues. Compression of tissues and the subsequent deformation of cells are just one type physical strain MSCs will need
Bolten, Zachary T., Hsieh, Adam H., Sharma, Poonam, Wagner, Diane R.   +3 more
core   +1 more source