Results 51 to 60 of about 13,553 (252)

Ivermectin for onchocercal eye disease (river blindness).

open access: yes, 2012
BACKGROUND: It is believed that ivermectin (a microfilaricide) could prevent blindness due to onchocerciasis. However, when given to everyone in communities where onchocerciasis is common, the effects of ivermectin on lesions affecting the eye are ...
Ejere, Henry OD   +3 more
core   +1 more source

The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models. [PDF]

open access: yes, 2016
Toll-like receptors (TLRs) play an important role in the innate and adaptive immune responses to pathogens, and are the target of new vaccine adjuvants.
Bates, PA   +4 more
core   +7 more sources

Comparison of Diagnostic Tests for Onchocerca volvulus in the Democratic Republic of Congo

open access: yesPathogens, 2020
Onchocerciasis is diagnosed by detecting microfilariae in skin snips or by detecting OV16 IgG4 antibodies in blood by either enzyme linked immunosorbent assay (ELISA) or a rapid diagnostic test (RDT).
An Hotterbeekx   +8 more
doaj   +1 more source

Immunopathological response of leukocytes against microfilariae and adult worms in white rats infected with Setaria cervi [PDF]

open access: yesVeterinary World, 2017
Aim: Aim of this study was to see the immunopathological changes against the microfilariae (Mf) and adult worms of a bovine filarid, Setaria cervi in the tissues of vital organs of experimentally infected white rats. The effect of diethylcarbamazine (DEC)
Sharba Kausar, Wajihullah Khan
doaj   +1 more source

Redescription of Cercopithifilaria bainae Almeida & Vicente, 1984 (Spirurida, Onchocercidae) from a dog in Sardinia, Italy [PDF]

open access: yes, 2013
Background Three species of the genus Cercopithifilaria have been morphologically and molecularly characterized in dog populations in southern Europe: Cercopithifilaria grassii (Noè, 1907), Cercopithifilaria sp.
Annoscia, Giada   +9 more
core  

The Role of Macrophages in Cancer: From Basic Research to Clinical Applications

open access: yesMedComm, Volume 7, Issue 1, January 2026.
Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu   +5 more
wiley   +1 more source

How can onchocerciasis elimination in Africa be accelerated? Modelling the impact of increased ivermectin treatment frequency and complementary vector control [PDF]

open access: yes, 2017
Background: Great strides have been made toward onchocerciasis elimination by mass drug administration (MDA) of ivermectin. Focusing on MDA-eligible areas, we investigated where the elimination goal can be achieved by 2025 by continuation of current ...
Afework H Tekle   +59 more
core   +5 more sources

Energetic and oxidative costs of microfilarial infection: evidence for fitness trade‐offs in male village weavers of the Amurum Forest Reserve

open access: yesWildlife Biology, Volume 2026, Issue 1, January 2026.
Microfilariae contribute to a higher energetic demand that could lead to oxidative damage and reduce hosts' fitness. Yet reports about the energy status and oxidative stress‐defense mechanisms of infected wild birds are rarely documented. We investigated the relationship between microfilariae and the energy status and oxidative damage‐defense ...
Felix A. Andong   +6 more
wiley   +1 more source

Blood Parasites and Wildlife: The Development of a Discipline

open access: yesIntegrative Zoology, Volume 21, Issue 1, Page 2-10, January 2026.
Changes in our knowledge on blood parasite infections of wild animals in the last 30 years is reviewed with emphasis on taxonomy and phylogeny, impact of infections on fitness, and distribution of blood parasites. ABSTRACT In the last 30 years, the area of the study of parasitism caused by blood parasite infections on wildlife has suffered an ...
Santiago Merino
wiley   +1 more source

Experimental Evidence That Blood Parasite Infection Affects Incubation Patterns in a Cavity‐Nesting Songbird

open access: yesIntegrative Zoology, Volume 21, Issue 1, Page 178-191, January 2026.
Chronic blood parasite infections in wild birds can affect their incubation behavior. In pied flycatchers, females with reduced parasite infections incubated for longer than control females. Despite behavioral changes, no immediate effects on fitness were observed.
Marina García‐del Río   +5 more
wiley   +1 more source

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