Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions
Advanced Healthcare Materials, EarlyView.Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi +7 more
wiley +1 more source
Application of microfluidic chip-based multiplex PCR in diagnosing reproductive tract pathogens among patients with premature rupture of membranes. [PDF]
Front Cell Infect MicrobiolZhang L, Shao Z.
europepmc +1 more source
Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering
Advanced Healthcare Materials, EarlyView.This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer +4 more
wiley +1 more source
Reagent‐Free Covalent Immobilization of Biomolecules in a Microfluidic Organ‐On‐A‐Chip (Adv. Funct. Mater. 30/2024) [PDF]
Deepu Ashok +4 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Microfluidic platform for understanding Parkinson's disease and α-synuclein conformation. [PDF]
Transl NeurodegenerPavel T +6 more
europepmc +1 more source
Correction: Corrigendum: A multi-functional bubble-based microfluidic system [PDF]
, 2018 Khashayar Khoshmanesh +5 more
openalex +1 more source
Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs
Advanced Healthcare Materials, EarlyView.Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller +5 more
wiley +1 more source
Parallel multiphysics simulations of charged particles in microfluidic flows [PDF]
, 2015 Dominik Bartuschat, Ulrich Rüde
openalex +1 more source