Results 121 to 130 of about 53,001 (261)

Liquid-infiltrated photonic crystals - enhanced light-matter interactions for lab-on-a-chip applications

, 2007
Optical techniques are finding widespread use in analytical chemistry for chemical and bio-chemical analysis. During the past decade, there has been an increasing emphasis on miniaturization of chemical analysis systems and naturally this has stimulated ...
A Sharkawy, C Monat, CJ Choi, D Erickson, D Janasek, D Psaltis, DA Skoog, E Chow, E Lidorikis, E Verpoorte, E Yablonovitch, E Yablonovitch, GM Whitesides, H Azzouz, H Kurt, H Kurt, J Topol’ančik, JD Joannopoulos, Jesper Pedersen, K Busch, K Sakoda, K Samakkulam, KB Mogensen, KB Mogensen, KJ Vahala, L Diehl, L Rindorf, M Born, M Gersborg-Hansen, M Hossein-Zadeh, M Lee, M Lončar, ML Adams, ML Gorodetsky, MM Sigalas, N Skivesen, NA Mortensen, NA Mortensen, NA Mortensen, Niels Asger Mortensen, P Domachuk, P Domachuk, P Mach, S Balslev, S Chakravarty, S John, S Tomljenovic-Hanic, S Xiao, Sanshui Xiao, SG Johnson, T Asano, T Hasek, T Prasad, T Yoshie, TM Squires, TT Larsen, U Levy, Y Akahane   +57 more
core   +1 more source

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Measurements and analysis of nitrogen and phosphorus in oceans: Practice, frontiers, and insights

Heliyon
Nitrogen and phosphorus concentrations in oceans have been extensively studied, and advancements in associated disciplines have rapidly progressed, enabling the exploration of novel and previously challenging questions.
Hasitha Siriwardana, R.S.M. Samarasekara, Damsara Anthony, Meththika Vithanage   +3 more
doaj   +1 more source

Spiropyran modified microfluidic chip channels for photonically controlled sensor array detection of metal ions [PDF]

, 2008
Microfluidic chips are particularly attractive for analytical purposes because they provide a convenient small platform for rapid analysis and detection.1 Furthermore, spiropyrans dyes can be used as photonically controlled, self-indicating molecular ...
Benito-Lopez, Fernando, Diamond, Dermot, Macka, Mirek, Paull, Brett, Scarmagnani, Silvia, Walsh, Zarah   +5 more
core  

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Biagio Palmisano, Silvia Franco, Roberta Angelini, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +14 more
wiley   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

BioScript: programming safe chemistry on laboratories-on-a-chip [PDF]

, 2018
This paper introduces BioScript, a domain-specific language (DSL) for programmable biochemistry which executes on emerging microfluidic platforms. The goal of this research is to provide a simple, intuitive, and type-safe DSL that is accessible to life ...
Brisk, Philip, Curtis, Chris, Lesani, Mohsen, Loveless, Tyson, Ott, Jason   +4 more
core  

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source