Results 271 to 280 of about 122,783 (311)

Microfluidic devices for diagnostic applications

Expert Review of Molecular Diagnostics, 2011
Microfluidic systems have become an attractive platform for diagnostic applications. The technology not only allows drastically decreased assay volumes (down to picoliters), but also accelerates sample processing and readout. In this article we give an overview of the different kinds of systems, ranging from non- or minimally instrumented point-of-care
Dominic, Eicher, Christoph A, Merten
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Step-emulsification in a microfluidic device

Lab on a Chip, 2015
We present a comprehensive theoretical and experimental study of the microfluidic step-emulsification process for high-throughput production of monodisperse droplets.
Z, Li, A M, Leshansky, S, Metais, L M, Pismen, P, Tabeling   +4 more
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Microfluidic devices for the analysis of apoptosis

ELECTROPHORESIS, 2005
AbstractApoptosis is the outcome of a metabolic cascade that results in cell death in a controlled manner. Due to its important role in maintaining balance in organisms, in mechanisms of diseases, and tissue homeostasis, apoptosis is of great interest in the emerging fields of systems biology.
Jianhua, Qin, Nannan, Ye, Xin, Liu, Bingcheng, Lin   +3 more
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Microfluidic Device for Localized Electroporation

2019
Electroporation is a common method of transfection due to its relatively low risk and high transfection efficiency. The most common method of electroporation is bulk electroporation which is easily performed on large quantities of cells yet results in variable levels of viability and transfection efficiency across the population.
Brooks, Justin, Jaberi, Arian, Yang, Ruiguo   +2 more
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Polyimide-based microfluidic devices

Lab on a Chip, 2001
This paper describes the development of polyimide-based microfluidic devices. A layer transfer and lamination technique is used to fabricate flexible microfluidic channels in various shapes and with a wide range of dimensions. High bond strengths can be achieved by cure cycle adaptation and surface treatment of the polyimide layers prior to bonding ...
Metz S, Holzer R, Renaud P
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Sample purification on a microfluidic device

ELECTROPHORESIS, 2001
Sample preparation has long been recognized as a significant barrier to the implementation of macroscopic protocols on microfabricated devices. Macroscopically, such tasks as removing salts, primers and other contaminants are performed by methods involving precipitation, specialized membranes and centrifuges, none of which are readily performed in ...
T, Footz, S, Wunsam, S, Kulak, H J, Crabtree, D M, Glerum, C J, Backhouse   +5 more
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Automatic Design of Microfluidic Devices

2018 Forum on Specification & Design Languages (FDL), 2018
This overview paper summarizes the content of a tutorial given at the 2018 edition of the Forum on specification & Design Languages. The aim of the tutorial was to introduce the technology of microfluidic devices, which gained significant interest in the recent past, as well as corresponding design challenges to a community focused on design automation
Robert Wille, Bing Li 0005, Rolf Drechsler, Ulf Schlichtmann   +3 more
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Monoliths for microfluidic devices in proteomics

Journal of Chromatography B, 2004
We report here on the preparation of monolithic capillary columns in view to their integration in a microsystem for on-chip sample preparation before their on-line analysis by electrospray and mass spectrometry (ESI-MS). These monolithic columns are based on polymer materials and consist of reverse phases for peptide separation and/or desalting.
Le Gac, S., Carlier, Julien, Camart, J.C., Cren-Olivé, C., Rolando, C.   +4 more
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Emerging paper microfluidic devices

The Analyst, 2019
Paper has unique advantages over other materials, including low cost, flexibility, porosity, and self-driven liquid pumping, thus making it widely used in various fields in biology, chemistry, physics and materials science.
Bingbing Gao, Xin Li, Yaqiong Yang, Jianlin Chu, Bingfang He   +4 more
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Functionalized Vesicles by Microfluidic Device

2017
In recent years, lipid vesicles have become popular vehicles for the creation of biosensors. Vesicles can hold reaction components within a selective permeable membrane that provides an ideal environment for membrane protein biosensing elements. The lipid bilayer allows a protein to retain its native structure and function, and the membrane fluidity ...
Derek, Vallejo, Shih-Hui, Lee, Abraham, Lee   +2 more
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