Results 41 to 50 of about 122,783 (311)

Slicing Spheroids in Microfluidic Devices for Morphological and Immunohistochemical Analysis

open access: yesMicromachines, 2020
Microfluidic devices utilizing spheroids play important roles in in vitro experimental systems to closely simulate morphological and biochemical characteristics of the in vivo tumor microenvironment.
Satoru Kuriu   +3 more
doaj   +1 more source

A Monolithically Fabricated Combinatorial Mixer for Microchip-Based High-Throughput Cell Culturing Assays [PDF]

open access: yes, 2007
We present an integrated method to fabricate 3- D microfluidic networks and fabricated the first on-chip cell culture device with an integrated combinatorial mixer.
Ho, Dean, Liu, Mike C., Tai, Yu-Chong
core   +1 more source

Chemical-Free Extraction of Functional Mitochondria Using a Microfluidic Device

open access: yesInventions, 2018
This paper proposes the use of a chip-based microfluidic device to extract functional and chemical free mitochondria. A simple microfluidic device was designed and fabricated. An osteosarcoma cybrid cell line was employed to demonstrate the efficiency of
Yu-Han Hsiao   +5 more
doaj   +1 more source

Development of Microdroplet Generation Method for Organic Solvents Used in Chemical Synthesis

open access: yesMolecules, 2020
Recently, chemical operations with microfluidic devices, especially droplet-based operations, have attracted considerable attention because they can provide an isolated small-volume reaction field.
Shohei Hattori   +8 more
doaj   +1 more source

Pump-Free Microfluidic Hemofiltration Device

open access: yesMicromachines, 2021
Hemofiltration removes water and small molecules from the blood via nanoporous filtering membranes. This paper discusses a pump-free hemofiltration device driven by the pressure difference between the artery and the vein.
Takahiro Ito   +8 more
doaj   +1 more source

Maintenance of head and neck tumor on-chip: gateway to personalized treatment? [PDF]

open access: yes, 2017
Aim: Head and neck squamous cell carcinomas (HNSCC) are solid tumors with low overall survival (40–60%). In a move toward personalized medicine, maintenance of tumor biopsies in microfluidic tissue culture devices is being developed. Methodology/ results:
Bower, Ruth   +7 more
core   +1 more source

A microfluidic chip based model for the study of full thickness human intestinal tissue using dual flow [PDF]

open access: yes, 2016
© 2016 Author(s). The study of inflammatory bowel disease, including Ulcerative Colitis and Crohn's Disease, has relied largely upon the use of animal or cell culture models; neither of which can represent all aspects of the human pathophysiology ...
A. Dawson   +11 more
core   +1 more source

An Integrated Artificial Cilia Based Microfluidic Device for Micropumping and Micromixing Applications

open access: yesMicromachines, 2017
A multi-purpose microfluidic device that can be used for both micromixing and micropropulsion operations has always been in demand, as it would simplify the various process flows associated with the current micro-total analysis systems.
Yu-An Wu   +3 more
doaj   +1 more source

Activation and Switching of Supramolecular Chemical Signals in Multi-Output Microfluidic Devices

open access: yesMicromachines, 2022
In this study, we report on the developing of a continuous microfluidic reaction device that allows selective activation of polyelectrolyte-surfactant chemical signals in microflows and switches them between multiple outputs.
Artem Bezrukov, Yury Galyametdinov
doaj   +1 more source

A Microfluidic Concentration Gradient Maker with Tunable Concentration Profiles by Changing Feed Flow Rate Ratios

open access: yesMicromachines, 2020
Microfluidic chips—in which chemical or biological fluid samples are mixed into linear or nonlinear concentration distribution profiles—have generated enormous enthusiasm of their ability to develop patterns for drug release and their ...
Tao Zhang   +6 more
doaj   +1 more source

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