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Microfluidic Paper-based Analytical Devices in Clinical Applications
Chromatographia, 2020Microfluidic paper-based analytical devices (µPADs) take the paper as a base material and integrate nanoscale microchannel on it for multiple detections. Its unique properties like low cost, portability, simple operation, and easy to save make it better than the traditional microfluidic chips.
Tingting Han +7 more
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Quantitative biomarker assay with microfluidic paper-based analytical devices
Analytical and Bioanalytical Chemistry, 2009This article describes the use of microfluidic paper-based analytical devices (muPADs) to perform quantitative chemical assays with internal standards. MicroPADs are well-suited for colorimetric biochemical assays; however, errors can be introduced from the background color of the paper due to batch difference and age, and from color measurement ...
Xu, Li, Junfei, Tian, Wei, Shen
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Comprehensive model of electromigrative transport in microfluidic paper based analytical devices
ELECTROPHORESIS, 2020AbstractA complete mathematical model for electromigration in paper‐based analytical devices is derived, based on differential equations describing the motion of fluids by pressure sources and EOF, the transport of charged chemical species, and the electric potential distribution.
Federico Schaumburg +2 more
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Recent Developments in Microfluidic Paper-based Analytical Devices for Pharmaceutical Analysis
Current Topics in Medicinal Chemistry, 2022Abstract: In the last decade, due to the global increase in diseases, drugs for biomedical applications have increased dramatically. Therefore, there is an urgent need for analytical tools to monitor, treat, investigate, and control drug compounds in diverse matrices.
Wisarut, Khamcharoen +5 more
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An Automated Microfluidic Paper-Based Analytical Device for Chemiluminescence Immunoassay
2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)This paper introduces a high-integrated microfluidic paper-based analytical device (μPAD) that has a reliable and programmable rotary valve and automated injection device. By controlling the rotation of valves, different regions on the μPAD can be connected or disconnected, allowing reagents to be effectively transported to the test zone.
Jihong Sun +8 more
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An integrated platform for fibrinogen quantification on a microfluidic paper-based analytical device
Lab on a Chip, 2020Fibrinogen (FIB) plays a key role in blood coagulation and thrombosis and its concentration in blood can directly reflect health conditions, thus an efficient detection of FIB would benefit the treatments of certain diseases such as liver and heart diseases.
Yanfang Guan +8 more
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Analytica Chimica Acta, 2016
A low cost, disposable and easy to use microfluidic paper-based analytical device (μPAD) was developed for simple and non-invasive determination of total aldehydes in saliva with a potential to be used in epidemiological studies to assess oral cancer risk. The μPAD is based on the colour reaction between aldehydes (e.g.
Adlin N. Ramdzan +3 more
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A low cost, disposable and easy to use microfluidic paper-based analytical device (μPAD) was developed for simple and non-invasive determination of total aldehydes in saliva with a potential to be used in epidemiological studies to assess oral cancer risk. The μPAD is based on the colour reaction between aldehydes (e.g.
Adlin N. Ramdzan +3 more
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Challenges in the development of microfluidic paper–based analytical devices (μPADs)
Microchimica ActaThe scientific and technological underpinnings of microfluidic paper-based analytical devices (μPADs), a field initiated by Whitesides' research group in 2007, pertain to the design and fabrication of analytical devices composed of paper or other porous membranes that manipulate minute fluid volumes (10-6 to 10-9 L) through the principle of capillary ...
Farshad, Ardakani, Bahram, Hemmateenejad
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Acid–Base Titrations Using Microfluidic Paper-Based Analytical Devices
Analytical Chemistry, 2014Rapid and simple acid-base titration was accomplished using a novel microfluidic paper-based analytical device (μPAD). The μPAD was fabricated by wax printing and consisted of ten reservoirs for reaction and detection. The reaction reservoirs contained various amounts of a primary standard substance, potassium hydrogen phthalate (KHPth), whereas a ...
Shingo, Karita, Takashi, Kaneta
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ACS Biomaterials Science & Engineering, 2017
As a kind of facile tool, microfluidic paper-based analytical devices (μPADs) have been widely used in analytical and biomedical fields. However, because we lack the ability to control the continuous perfusion of these devices, they are not generally used in fields that require continuous flow, especially biofluidics fields such as cell culturing, drug
Yan Wu +4 more
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As a kind of facile tool, microfluidic paper-based analytical devices (μPADs) have been widely used in analytical and biomedical fields. However, because we lack the ability to control the continuous perfusion of these devices, they are not generally used in fields that require continuous flow, especially biofluidics fields such as cell culturing, drug
Yan Wu +4 more
openaire +2 more sources