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Although the field of microfluidics has made significant progress in bringing new tools to address biological questions, the accessibility and adoption of microfluidics within the life sciences are still limited. Open microfluidic systems have the potential to lower the barriers to adoption, but the absence of robust design rules has hindered their use.
Benjamin P, Casavant +10 more
openaire +2 more sources
A Parametric Study on a Paper-Based Bi-Material Cantilever Valve
The novel paper-based Bi-Material Cantilever (B-MaC) valve allows the autonomous loading and control of multiple fluid reagents which contributes to the accurate operation of paper-based microfluidic devices utilized for biological and chemical sensing ...
Hojat Heidari-Bafroui +6 more
doaj +1 more source
Testing microelectronic biofluidic systems [PDF]
According to the 2005 International Technology Roadmap for Semiconductors, the integration of emerging nondigital CMOS technologies will require radically different test methods, posing a major challenge for designers and test engineers.
Kerkhoff, Hans G.
core +4 more sources
AbstractA cross‐comparison of three stop‐flow configurations—such as low‐pressure (LSF), high‐pressure open‐circuit (OC‐HSF), and high‐pressure short‐circuit (SC‐HSF) stop‐flow—is presented to rapidly bring a high velocity flow O(m s−1) within a microchannel to a standstill O(µm s−1).
Mehmet Akif Sahin +2 more
openaire +4 more sources
Microfluidics: an enabling technology for the life sciences [PDF]
During the last year we have investigated existing and future markets, products and technologies for microfluidics in the life sciences. Within this paper we present some of the findings and discuss a major trend identified within this project: the ...
Ducrée, Jens +2 more
core +1 more source
Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia [PDF]
This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfluidic approach.
Brognara, Eleonora +8 more
core +2 more sources
Microfluidics platforms can program small amounts of fluids to execute a bio-protocol, and thus, can automate the work of a technician and also integrate a large part of laboratory equipment. Although most microfluidic systems have considerably reduced the size of a laboratory, they are still benchtop units, of a size comparable to a desktop computer ...
openaire +4 more sources
Microfluidic Contact Lenses [PDF]
AbstractContact lens is a ubiquitous technology used for vision correction and cosmetics. Sensing in contact lenses has emerged as a potential platform for minimally invasive point‐of‐care diagnostics. Here, a microlithography method is developed to fabricate microconcavities and microchannels in a hydrogel‐based contact lens via a combination of laser
Nan Jiang +3 more
openaire +5 more sources
A Microfluidic Biodisplay [PDF]
AbstractSynthetically engineered cells are powerful and potentially useful biosensors, but it remains problematic to deploy such systems due to practical difficulties and biosafety concerns. To overcome these hurdles, we developed a microfluidic device that serves as an interface between an engineered cellular system, environment, and user.
Francesca Volpetti +2 more
openaire +2 more sources
Microfluidics: Fluid physics at the nanoliter scale [PDF]
Microfabricated integrated circuits revolutionized computation by vastly reducing the space, labor, and time required for calculations. Microfluidic systems hold similar promise for the large-scale automation of chemistry and biology, suggesting the ...
Quake, Stephen R., Squires, Todd M.
core +1 more source

