Results 41 to 50 of about 87,442 (257)

Chemical Synthesis in Elastomer-Based Integrated Microfluidics [PDF]

, 2010
There is wide interest in using the unique properties of microfluidic environments for the production of fine chemicals and pharmaceuticals. Compared to bench top synthesis, microfluidic systems engender the significant advantage of superior control of ...
Cheng-chung Lee, Lee, Cheng-Chung
core   +1 more source

Mechanical Properties of Stainless-Steel Structures Fabricated by Composite Extrusion Modelling

Metals, 2018
Composite Extrusion Modelling (CEM) is a new additive manufacturing process for metal that uses Metal Injection Moulding (MIM) materials. The MIM material is printed on a build plate using a moveable extruder.
Clemens Lieberwirth, Mohamed Sarhan, Hermann Seitz   +2 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Modeling of Paper-Based Bi-Material Cantilever Actuator for Microfluidic Biosensors

Biosensors, 2023
This research explores the dynamics of a fluidically loaded Bi-Material cantilever (B-MaC), a critical component of μPADs (microfluidic paper-based analytical devices) used in point-of-care diagnostics.
Ashutosh Kumar, Hojat Heidari-Bafroui, Nassim Rahmani, Constantine Anagnostopoulos, Mohammad Faghri   +4 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Viscoelastic microfluidics: Fundamentals, technological development and applications [PDF]

Microfluidics has significantly advanced research in environmental science, biomedicine, and chemical analysis. Many natural and synthetic fluids, such as saliva, blood and polymer solution, are non-Newtonian.
Nguyen, Nam-Trung, Cha, Haotian, Yuan, Dan, Klimenko, Alexander, Li, Weihua, Zhang, Jun, Kang, Xiaoyue   +6 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip

Stem Cell Research & Therapy
Background The differentiation of pluripotent stem cells (PSCs) and their self-organization into organoids are influenced by cell-cell interactions mediated by contacts and secreted molecules.
Nadia Vertti-Quintero, Clara Delahousse, Andrey Aristov, Tatiana Traboulsi, Jack-Christophe Cossec, Charles N. Baroud, Sébastien Sart   +6 more
doaj   +1 more source

Experimental studies on 3D printing of barium titanate ceramics for medical applications

Current Directions in Biomedical Engineering, 2016
The present work deals with the 3D printing of porous barium titanate ceramics. Barium titanate is a biocompatible material with piezoelectric properties.
Schult Mark, Buckow Eric, Seitz Hermann
doaj   +1 more source