Results 51 to 60 of about 87,442 (257)

Cell Patterning Technology on Polymethyl Methacrylate through Controlled Physicochemical and Biochemical Functionalization

Biosensors, 2023
In recent years, innovative cell-based biosensing systems have been developed, showing impact in healthcare and life science research. Now, there is a need to design mass-production processes to enable their commercialization and reach society.
Enrique Azuaje-Hualde, Job Komen, Juncal A. Alonso-Cabrera, Albert van den Berg, Marian M. de Pancorbo, Andries D. van der Meer, Fernando Benito-Lopez, Lourdes Basabe-Desmonts   +7 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Development of a New Lab-on-Paper Microfluidics Platform Using Bi-Material Cantilever Actuators for ELISA on Paper

Biosensors, 2023
In this paper, we present a novel and cost-effective lab-on-paper microfluidics platform for performing ELISA autonomously, with no user intervention beyond adding the sample.
Hojat Heidari-Bafroui, Ashutosh Kumar, Cameron Hahn, Nicholas Scholz, Amer Charbaji, Nassim Rahmani, Constantine Anagnostopoulos, Mohammad Faghri   +7 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Automated Microfluidic Platform for Molecular Transport Analysis across Biomimetic Interfaces

Advanced Sensor Research
Advancing drug development and disease modeling requires physiologically relevant in vitro systems that accurately reproduce the dynamic and selective transport functions of human tissue barriers.
Olivier Fournier, Miguel A. D. Neves, Théo Gavoille, Alan Morin, Beatriz Pais, Ivana Brenta, Justine Lereculey‐Beaumanoir, Andrea Cruz, Denis Santos, Hugo Oliveira, Michael Gasik, Lisa D. Muiznieks, Inês Mendes Pinto   +12 more
doaj   +1 more source

Paper-Based Bi-Material Cantilever Actuator Bending Behavior and Modeling

Micromachines, 2023
In this paper, the behavior of the Bi-Material Cantilever (B-MaC) response deflection upon fluidic loading was experimentally studied and modeled for bilayer strips. A B-MaC consists of a strip of paper adhered to a strip of tape.
Gordon Chen, Ashutosh Kumar, Hojat Heidari-Bafroui, Winfield Smith, Amer Charbaji, Nassim Rahmani, Constantine Anagnostopoulos, Mohammad Faghri   +7 more
doaj   +1 more source

Fabrication Routes for Ionic Conducting Fiber Strain Sensors

Advanced Engineering Materials, EarlyView.
Ionic conducting fiber strain sensors (ICFSs) offer compliant, textile‐integrable sensing. Thus far, the commercialization of ICFSs has been constrained by fiber fabrication routes. This review provides a fabrication‐centric analysis of ICFSs correlating processing strategies with material properties and scalability.
Leo John Kershaw, Zhanhong Yang, Anne Ladegaard Skov, Magdalena Skowyra   +3 more
wiley   +1 more source

Basic Technologies for Droplet Microfluidics

, 2011
Basic Technologies for Droplet MicrofluidicsIn recent years droplet microfluidics has become a quickly evolving research field. The availability of a wide range of technologies for droplet generation and manipulation has enabled the applications of ...
林炳承, Xie, Hua, Liu, Xin, Zeng, Shaojiang, Lin, Bingcheng, Lin, BC   +5 more
core   +1 more source

Distance-based ratio metric assay using thread-based devices for Karaya gum detection in food samples

Scientific Reports
Karaya gum, a natural food-grade thickener, is an adulterant that compromises product quality and consumer safety. Herein, we develop a low-cost, rapid and portable device that employs thread-based microfluidics integrated with ratio-metric displacement ...
Reshmi Saravana Bhava, Anusha Prabhu, Balachandar Sundarrajan, Shashanka Puranika Kota, Naresh Kumar Mani   +4 more
doaj   +1 more source

Digital Light Processing of Thermoplastic Poly(methyl methacrylate) Photoresin Combined With Solvent Vapor Smoothing

Advanced Engineering Materials, EarlyView.
A thermoplastic PMMA‐based photoresin enables high‐resolution DLP printing followed by solvent‐vapor smoothing. The treatment reduces staircase‐induced surface roughness from 2.33 µm to 129 nm and increases visible‐light transmittance from approximately 30% to 80%, providing a route toward transparent PMMA components for rapid prototyping and non ...
Rozhin Heydarpour, Yuanyuan Li, Sebastian Kluck, Afnan Quazzie‐Hauser, Bastian E. Rapp, Frederik Kotz‐Helmer   +5 more
wiley   +1 more source