Results 51 to 60 of about 118,476 (281)

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Mechanical Properties of Stainless-Steel Structures Fabricated by Composite Extrusion Modelling

Metals, 2018
Composite Extrusion Modelling (CEM) is a new additive manufacturing process for metal that uses Metal Injection Moulding (MIM) materials. The MIM material is printed on a build plate using a moveable extruder.
Clemens Lieberwirth, Mohamed Sarhan, Hermann Seitz   +2 more
doaj   +1 more source

Paper-Based Bi-Material Cantilever Actuator Bending Behavior and Modeling

Micromachines, 2023
In this paper, the behavior of the Bi-Material Cantilever (B-MaC) response deflection upon fluidic loading was experimentally studied and modeled for bilayer strips. A B-MaC consists of a strip of paper adhered to a strip of tape.
Gordon Chen, Ashutosh Kumar, Hojat Heidari-Bafroui, Winfield Smith, Amer Charbaji, Nassim Rahmani, Constantine Anagnostopoulos, Mohammad Faghri   +7 more
doaj   +1 more source

Digital microfluidics with pressure-based actuation [PDF]

, 2013
One of the key issues in biosensors is the time it takes for biomolecules in a solution to reach and bind to the sensor surface (particularly in low-concentration analytes).
Bienstman, Peter, Hallynck, Elewout
core   +2 more sources

Biomimetic Iridescent Skin: Robust Prototissues Spontaneously Assembled from Photonic Protocells

Advanced Functional Materials, EarlyView.
Uniform nanoparticles are induced to form arrays (photonic crystals) in the cores of biopolymer capsules, endowing these ‘protocells’ with structural color. These protocells are then assembled into large self‐standing objects, i.e., prototissues, with robust mechanical properties as well as iridescent optical properties.
Medha Rath, Briahnah Streeter, Satyam Srivastava, Jemma Wood, William E. Bentley, Taylor J. Woehl, Srinivasa R. Raghavan   +6 more
wiley   +1 more source

Cell Patterning Technology on Polymethyl Methacrylate through Controlled Physicochemical and Biochemical Functionalization

Biosensors, 2023
In recent years, innovative cell-based biosensing systems have been developed, showing impact in healthcare and life science research. Now, there is a need to design mass-production processes to enable their commercialization and reach society.
Enrique Azuaje-Hualde, Job Komen, Juncal A. Alonso-Cabrera, Albert van den Berg, Marian M. de Pancorbo, Andries D. van der Meer, Fernando Benito-Lopez, Lourdes Basabe-Desmonts   +7 more
doaj   +1 more source

Development of flow focusing device for the visualization of leukocyte rolling adhesion [PDF]

, 2018
La microfluídica es un área de la microtecnología basada en chips de PDMS que está siendo utilizada cada vez más en multitud de aplicaciones. Una de estas aplicaciones es la investigación biomédica.
Morales Navarrete, Pablo
core  

A robotics platform for automated batch fabrication of high density, microfluidics-based DNA microarrays, with applications to single cell, multiplex assays of secreted proteins [PDF]

, 2011
Microfluidics flow-patterning has been utilized for the construction of chip-scale miniaturized DNA and protein barcode arrays. Such arrays have been used for specific clinical and fundamental investigations in which many proteins are assayed from single
Ahmad, Habib, Heath, James R., Hwang, Kiwook, Krom, Russell-John, Qin, Lidong, Shin, Young Shik, Sutherland, Alex   +6 more
core   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip

Stem Cell Research & Therapy
Background The differentiation of pluripotent stem cells (PSCs) and their self-organization into organoids are influenced by cell-cell interactions mediated by contacts and secreted molecules.
Nadia Vertti-Quintero, Clara Delahousse, Andrey Aristov, Tatiana Traboulsi, Jack-Christophe Cossec, Charles N. Baroud, Sébastien Sart   +6 more
doaj   +1 more source