Results 321 to 330 of about 388,044 (340)

Microglia-orchestrated neuroinflammation and synaptic remodeling: roles of pro-inflammatory cytokines and receptors in neurodegeneration. [PDF]

Front Cell Neurosci
Yang G, Xu X, Gao W, Wang X, Zhao Y, Xu Y.   +5 more
europepmc   +1 more source

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

Advanced Science, EarlyView.
Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian, Yun Chen, Jingyi Zhou, Shilin Zhang, Hongrui Fan, Xuwen Li, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

Human microglia differentially respond to β-amyloid, tau, and combined Alzheimer's disease pathologies in vivo. [PDF]

Alzheimers Dement
Coburn MA, Eskandari-Sedighi G, Hasselmann J, England W, Shabestari SK, Mansour K, McQuade A, Mgerian MA, Chadarevian JP, Tu C, Silva J, Beck J, Keulen Z, Spitale RC, Davtyan H, Blurton-Jones M.   +15 more
europepmc   +1 more source

Regulation of microglia and monocyte function by the cytokine TGF-beta

, 2018
Harald Lund
openalex  

Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice

Mariana Alves, Beatriz Gil, Javier Villegas-Salmerón, Valentina Salari, Ricardo Martins-Ferreira, Marina Blázquez‐García, Aida Menéndez Méndez, Rogerio Da Rosa Gerbatin, Jonathon Smith, Laura de Diego-García, Giorgia Conte, Juan Sierra-Marquez, Paula Merino Serrais, Meghma Mitra, Ana Fernandez Martin, Yitao Wang, Jaideep Kesavan, Ciara Melia, Alberto Parras, Edward Beamer, Béla Zimmer, Mona Heiland, Brenton Cavanagh, Rafael Parcianello Cipolat, James J. Morgan, Xinchen Teng, Jochen H.M. Prehn, Paolo Francesco Fabene, Giuseppe Bertini, Antonio R. Artalejo, Esteban Ballestar, Annette Nicke, Luis Alcides Olivos-Oré, Niamh M. C. Connolly, David C. Henshall, Tobías Engel   +35 more
openalex   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

Transcription Factor-Based Differentiation of Pluripotent Stem Cells: Overcoming the Traps of Random Neuronal Fate. [PDF]

Biomedicines
McDaid G, Vanek J, Cromer B, Sumer H.
europepmc   +1 more source

Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway. [PDF]

FASEB J
Ren L, Chen Y, Xia J, Song X, Tao L, Li J, Xu L, Lü H, Hu J.   +8 more
europepmc   +1 more source

Immune subversion by Leishmania infantum parasites suppresses NLRP3-driven inflammatory responses in amyloid-β-activated microglia. [PDF]

J Neuroinflammation
Calvo Alvarez E, Sfogliarini C, La Rosa F, Saresella M, Dolci M, Vegeto E, Taramelli D, Basilico N, Clerici M.   +8 more
europepmc   +1 more source

Disease-associated microglia in neurodegenerative diseases: Friend or foe? [PDF]

PLoS Biol
Cheng YH, Ho MS.
europepmc   +1 more source