Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin +8 more
wiley +1 more source
The Effects of Microgravity on Differentiation and Regeneration in Neural Stem Cells. [PDF]
Hao Q +5 more
europepmc +1 more source
Science of omics: a molecular space odyssey
Experimental Physiology, EarlyView.
Salomé Coppens +3 more
wiley +1 more source
Physiologic changes in microgravity may lead to unpredictable effects of spinal anesthesia. [PDF]
Wagner S, Turnock M.
europepmc +1 more source
The ultimate exercise countermeasure for long‐duration spaceflight?
Experimental Physiology, EarlyView.
Donald E. Watenpaugh, Alan R. Hargens
wiley +1 more source
Gait analysis for functional evaluation in a surgical hindlimb suspension model of muscle atrophy
Abstract figure legend Gait analysis reveals neuromuscular dysfunction following hindlimb suspension and partial recovery after reloading. Schematic overview of the experimental design and principal findings. Mice underwent 14 days of hindlimb suspension (HLS), resulting in muscle atrophy marked by reduced fiber size, satellite cell loss, and decreased
Yanping Xu +13 more
wiley +1 more source
PIEZO1 Mediates Apoptosis of Endothelial Cells via Enhancing HMGA2 Expression Under Simulated Microgravity. [PDF]
Wang Y +5 more
europepmc +1 more source
The Final Frontier: Toward Transformative Insights into the Pathophysiologic Adaptations to Microgravity with Molecular Imaging. [PDF]
Jadvar H.
europepmc +1 more source
Watching the eye with Mars in sight
Experimental Physiology, EarlyView.
Peter zu Eulenburg +2 more
wiley +1 more source
A computational model for retinal haemodynamics under gravitational and postural variations
Abstract figure legend The haemodynamic impact of gravitational and postural changes on the retina, and its relevance to spaceflight associated neuro‐ocular syndrome (SANS), remains incompletely characterized. This study assesses retinal haemodynamics from upright to head‐down tilt using a lumped‐parameter model that dynamically couples intraocular ...
Michele Nigro +2 more
wiley +1 more source

