Results 101 to 110 of about 55,411 (278)

Impact of 14 days of head‐down bed rest and an exercise countermeasure on skeletal muscle atrophy, proteome and circulatory cytokines in older adults

Experimental Physiology, EarlyView.
Abstract Prolonged bed rest and immobilization have deleterious effects on skeletal muscle mass and function, especially in older adults. These can lead to reduced physical capacity and quality of life. Previous experiments in younger individuals show that exercise can mitigate these effects, but evidence remains scarce and inconclusive in older adults.
Jean‐Christophe Lagacé, Philippe St‐Martin, Mariano Avino, Ahmed Ghachem, Guy Hajj‐Boutros, Jose A. Morais, Jamie S. McPhee, Karen Lambert, Eléonor Riesco, Isabelle J. Dionne   +9 more
wiley   +1 more source

Sessile Drop in Microgravity: Creation, Contact Angle and Interface

, 2009
We present in this paper the results obtained from a parabolic flight campaign regarding the contact angle and the drop interface behavior of sessile drops created under terrestrial gravity (1g) or in microgravity (mu g).
Tadrist L, Rahli O, Brutin D, 朱志强, 解京昌, 刘秋生   +5 more
core   +1 more source

Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite

Frontiers in Physiology, 2018
Endothelial cells (ECs) are mechanosensitive cells undergoing morphological and functional changes in space. Ground-based study has provided a body of evidences about how ECs can respond to the effect of simulated microgravity, however, these results ...
Ning Li, Ning Li, Chengzhi Wang, Chengzhi Wang, Shujin Sun, Shujin Sun, Chen Zhang, Chen Zhang, Dongyuan Lü, Dongyuan Lü, Qin Chen, Qin Chen, Mian Long, Mian Long   +13 more
doaj   +1 more source

Quantitative MRI changes in neck muscle size and composition following long‐duration spaceflight

Experimental Physiology, EarlyView.
Abstract Long‐duration spaceflight poses several challenges to human health, including muscle loss and fat deposition. To mitigate these effects, exercise countermeasures are prescribed. This study aimed to measure neck muscle size and composition changes with long‐duration spaceflight using quantitative magnetic resonance imaging (MRI) and examine ...
Diana A. Madrid Fuentes, Marina S. Sawires, Leon Lenchik, Janet A. Tooze, Ashley A. Weaver   +4 more
wiley   +1 more source

Analysis of the Dynamical Environment characterising the USV FTB_1 Vehicle performing the first DTFT Mission [PDF]

, 2006
The successfully realisation of a microgravity experiment, whatever its objective could be, necessarily requires a dynamical characterisation of the environment in which it takes place as complete and precise as possible.
Russo, Michelangelo
core   +1 more source

Putting the brakes on muscle growth: Myostatin as regulator of disuse atrophy

Experimental Physiology, EarlyView.
Abstract Skeletal muscle is a highly plastic tissue that rapidly adapts to changes in mechanical loading and metabolic activity. Periods of inactivity, including bed rest, limb immobilization or microgravity, induce a pronounced loss of muscle mass and function.
Derk H. C. Nieuwenhuijsen, Moritz Eggelbusch, Rob C. I. Wüst   +2 more
wiley   +1 more source

Effects of 14 days of head‐down bed rest with or without exercise, and subsequent recovery on bone turnover, density and structure in older adults

Experimental Physiology, EarlyView.
Abstract Bed rest accelerates bone loss and may exacerbate skeletal fragility. This study examined the effects of 14 days of head‐down tilt bed rest (HDBR) with or without exercise, and subsequent recovery, on bone turnover, density and structure in older adults. Twenty‐two healthy older adults (55–65 years) completed the HDBR protocol.
Guy Hajj‐Boutros, Andréa Faust, Carmelo Mastrandrea, Vita Sonjak, Dounia Rouabhia, Gustavo Duque, Richard Kremer, Stéphanie Chevalier, Julie Lacombe, Mathieu Ferron, Tyler A. Churchward‐Venne, José A. Morais   +11 more
wiley   +1 more source

Modelling large scale artery haemodynamics from the heart to the eye in response to simulated microgravity

We investigated variations in haemodynamics in response to simulated microgravity across a semi-subject-specific three-dimensional (3D) continuous arterial network connecting the heart to the eye using computational fluid dynamics (CFD) simulations ...
Parker, Louis P.,, Caddy, Harrison T.,, Green, Daniel J.,, Kelsey, Lachlan J.,, Doyle, Barry J.,   +4 more
core   +1 more source

Gas–Solid Phase Separation of Active Brownian Particles Under Confinement of Hard Walls

Nanomaterials
By means of computer simulations, we have investigated the gas–solid phase separation of active Brownian particles (ABPs) under the confinement of two hard walls, distinct from the gas–liquid phase separation typically seen in bulk systems.
Hao Zhang, Shenghua Xu, Shuangyang Zou, Hongwei Zhou, Wenze Ouyang, Jun Zhong   +5 more
doaj   +1 more source

Effects of 1 Gray radiation on the biophysical properties of the tibia and femur from hindlimb‐suspended rats

Experimental Physiology, EarlyView.
Abstract Long‐term space travel (e.g. travel to Mars) will greatly exceed the recommended lifetime radiation dose of 600 millisieverts (mSv) and have a detrimental effect on skeletal fragility. Our objective was to determine if 1 Gray (GY) radiation impacts the biomechanical properties of the tibia and femur from rats under microgravity.
Brent J. F. Hill, Rahul Mehta
wiley   +1 more source