Results 111 to 120 of about 54,337 (284)
An experimentally informed computational model of neurovestibular adaptation to altered gravity
Experimental Physiology, EarlyView.Abstract Transitions to altered gravity environments result in acute sensorimotor impairment for astronauts, leading to serious mission and safety risks in the crucial first moments in a new setting. Our understanding of the time course and severity of impairment in the early stages of adaptation remains limited and confounded by unmonitored head ...
Victoria G. Kravets, Torin K. Clark
wiley +1 more source
Experimental Physiology, EarlyView.Abstract A reduction in cerebral blood flow (CBF) has been observed during spaceflight and bed rest. We aimed to examine the magnitude and regional heterogeneity of the decrease in CBF during bed rest compared to posture changes on Earth. Seventeen participants (age, 29 ± 9 years, 7 females) were studied in the upright and supine posture and over 3 ...
Carmen Possnig +8 more
wiley +1 more source
The Effects of Microgravity on the Structure and Function of Cardiomyocytes
BiomoleculesSpaceflight and microgravity (μg) environments induce numerous cardiovascular changes that affect cardiac structure and function, and understanding these effects is essential for astronaut health and tissue engineering in space.
Luis Fernando González-Torres +2 more
doaj +1 more source
In vivo nuclear magnetic resonance imaging [PDF]
A number of physiological changes have been demonstrated in bone, muscle and blood after exposure of humans and animals to microgravity. Determining mechanisms and the development of effective countermeasures for long duration space missions is an ...
Bryan, R. N. +5 more
core +1 more source
Experimental Physiology, EarlyView.Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley +1 more source
Jumping on the moon as a potential exercise countermeasure
Experimental Physiology, EarlyView.Abstract The Moon's gravitational field strength (17% Earth's gravity) may facilitate the use of bodyweight jumping as an exercise countermeasure against musculoskeletal and cardiovascular deconditioning in reduced gravity settings. The present study characterised the acute physiological and kinetic responses to bodyweight jumping in simulated Lunar ...
Patrick Swain +4 more
wiley +1 more source
Omics Investigations of Prostate Cancer Cells Exposed to Simulated Microgravity Conditions
BiomoleculesProstate cancer (PC) is the most diagnosed cancer in males across the globe. Following the formation of metastasis, PC is linked to a notable decline in both prognosis and survival rates.
Herbert Schulz +11 more
doaj +1 more source
Experimental Physiology, EarlyView.Abstract Manned space exploration to distant destinations, including Mars, continues to be an aspiration of humankind. Space travel does, however, present many challenges to the body, amongst which adaptation to microgravity is perhaps the largest. For instance, both short and long manned spaceflight missions have shown substantial deleterious effects ...
Gerard McMahon +2 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Prolonged exposure to weightlessness leads to loss of muscle and bone mass. Therefore, astronauts on board the International Space Station (ISS) currently perform mandatory daily exercises. ISS missions usually last 6 months, and future missions will become significantly longer when going, for example, to Mars.
Jonas Böcker +6 more
wiley +1 more source