Results 31 to 40 of about 11,172 (243)

The economics of microgravity research [PDF]

npj Microgravity, 2015
In this introduction to the economics of microgravity research, DiFrancesco and Olson explore the existing landscape and begin to define the requirements for a robust, well-funded microgravity research environment. This work chronicles the history, the opportunities, and how the decisions made today will shape the future.
DiFrancesco, Jeanne M, Olson, John M
openaire   +2 more sources

Cytoskeletal Tensegrity in Microgravity [PDF]

Life, 2021
In order for Man to venture further into Space he will have to adapt to its conditions, including microgravity. Life as we know it has evolved on Earth with a substantial gravitational field. If they spend considerable time away from Earth, astronauts experience physiological, mental, and anatomical changes. It is not clear if these are pathological or
openaire   +3 more sources

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

Dependence of cyanobacterium growth and Mars-specific photobioreactor mass on total pressure, pN2 and pCO2

npj Microgravity
In situ resource utilization systems based on cyanobacteria could support the sustainability of crewed missions to Mars. However, their resource-efficiency will depend on the extent to which gases from the Martian atmosphere must be processed to support ...
Cyprien Verseux, Tiago P. Ramalho, Emma Bohuon, Nils Kunst, Viktoria Lang, Christiane Heinicke   +5 more
doaj   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

120 W Efficient Single Frequency Amplification Based on Wide Tunable 1018 nm DBR Seed Source

IEEE Photonics Journal
High-power, widely tunable 1018 nm single-frequency fiber lasers and their harmonics play a crucial role in Rydberg microwave measurement applications. This study focuses on the development of a high-power 1018 nm single-frequency narrow-linewidth fiber ...
Pan Li, Linfeng Li, Kaiming Cao, Ruihong Gao, Heshan Liu, Meng Shi, Ziren Luo   +6 more
doaj   +1 more source

Reconfigurable Design and Optimization‐Based Control of an Integrated Leg‐Arm Robot for Space Applications With an Underactuated Body

Advanced Intelligent Systems, EarlyView.
A quadrupedal integrated leg‐arm robot with an underactuated reconfigurable body is developed. By using a Sarrus mechanism as the body, the robot enables reconfiguration through its supporting limbs, achieving mode switching without additional actuators.
Xinghan Zhuang, Kun Xu, Shutao Wu, Haoyuan Liu, Bochao Song, Jiawei Chen, Peijin Zi, Tao Zhang, Xilun Ding   +8 more
wiley   +1 more source

Additive manufacturing-induced anisotropy in damping performance of a dual-phase high-entropy alloy

Journal of Materials Research and Technology
Additive manufacturing (AM) can endow materials with specific microstructures, inducing anisotropy. In this study, we employed the AM technique to fabricate a dual-phase high-entropy alloy (HEA) and evaluated the damping properties of this alloy cut ...
Yadong Li, Yunjian Bai, Zishang Liu, Quanyu Jiang, Kun Zhang, Bingchen Wei   +5 more
doaj   +1 more source

Simulated microgravity compromises mouse oocyte maturation by disrupting meiotic spindle organization and inducing cytoplasmic blebbing. [PDF]

PLoS ONE, 2011
In the present study, we discovered that mouse oocyte maturation was inhibited by simulated microgravity via disturbing spindle organization. We cultured mouse oocytes under microgravity condition simulated by NASA's rotary cell culture system, examined ...
Changli Wu, Xinzheng Guo, Fang Wang, Xiaoshuang Li, X Cindy Tian, Li Li, Zhenfang Wu, Shouquan Zhang   +7 more
doaj   +1 more source

Quasi-Periodic Oscillatory Motion of Particles Orbiting a Distorted, Deformed Compact Object

Universe, 2021
This work explores the dynamic properties of test particles surrounding a distorted, deformed compact object. The astrophysical motivation was to choose such a background as to constitute a more reasonable model of a real situation that arises in the ...
Shokoufe Faraji, Audrey Trova
doaj   +1 more source