Results 101 to 110 of about 59,493 (294)

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez   +4 more
wiley   +1 more source

Microinjection for precision genome editing in Caenorhabditis elegans

open access: gold, 2021
Krishna S. Ghanta   +2 more
openalex   +1 more source

Epilepsy surgery: From bench to the clinics

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Peach Kernel Oil Modulates Lipid Metabolism Disorder in ApoEa CRISPR/Cas9 Gene‐Disrupted Zebrafish

open access: yesFood Frontiers, EarlyView.
In this study, we used CRISPR/Cas9 gene editing technology to establish a lipid metabolism disorder model of ApoEa mutant zebrafish. We applied peach kernel oil to this model and studied the mechanism of peach kernel oil regulating lipid disorder in combination with transcriptomics.
Lei Xia   +14 more
wiley   +1 more source

An Easily Constructed Pipette for Pressure Microinjections Into the Brain

open access: hybrid, 1997
Igor Kratskin   +2 more
openalex   +1 more source

The problems of spermatid microinjection in the human: the need for an accurate morphological approach and selective methods for viable and normal cells [PDF]

open access: bronze, 1998
Pierre Vanderzwalmen   +7 more
openalex   +1 more source

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