Results 131 to 140 of about 59,493 (294)

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Trigeminal root demyelination is sufficient to induce trigeminal neuralgia-like facial pain in adult rodents. [PDF]

J Headache Pain
Wang ZY, Ding YQ, Wen JM, Zheng BW, Zhang K, Qi JG.   +5 more
europepmc   +1 more source

Establishment of a CRISPR/Cas9-Based Genome Editing System in <i>Macrobrachium rosenbergii</i>. [PDF]

Animals (Basel)
Yan J, Qian S, Li G, Liu Y, Zhou L, Ye T, Liu C, Meng J, Jie Y, Gu Z.   +9 more
europepmc   +1 more source

Aggression-reducing effects of F15599, a novel selective 5-HT1A receptor agonist, after microinjection into the ventral orbital prefrontal cortex, but not in infralimbic cortex in male mice

, 2013
Dirson João Stein, Klaus A. Miczek, Aldo Bolten Lucion, Rosa M. M. de Almeida   +3 more
openalex   +1 more source

Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis

Cell Proliferation, EarlyView.
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang, Rui Sun, Zhibin Lan, Qi Ma, Gang Wu, Di Xue, Zhirong Chen, Yajing Su, Ye Ma, Xiaolei Chen, Jiangbo Yan, Long Ma, Xiaoxin He, Kuanmin Tian, Xiaoyi Ma, Xue Lin, Qunhua Jin   +16 more
wiley   +1 more source

High-Humidity Incubation Improves Post-Microinjection Viability and Larval Performance of CRISPR/Cas9-Edited <i>Helicoverpa armigera</i> Embryos. [PDF]

Insects
Zhu J, Li H, Peng Y, Jin M, Mao K, Xiao Y.   +5 more
europepmc   +1 more source

NMDA receptor antagonism blocks the cardiovascular responses to microinjection of trans‐ACPD into the NTS of awake rats [PDF]

, 2004
Vagner Roberto Antunes, Leni G. H. Bonagamba, Benedito H. Machado   +2 more
openalex   +1 more source

Kdf1 Regulates Molar Cusp Morphogenesis via the PI3K/AKT/mTOR Signalling Axis

Cell Proliferation, EarlyView.
Epithelial Kdf1 knockout disrupts molar cusp morphogenesis by promoting inner enamel epithelium proliferation and invagination via PI3K/AKT/mTOR signalling. ABSTRACT Keratinocyte differentiation factor 1 (Kdf1) reportedly plays a significant role in enamel formation.
Jiayu Wang, Miao Yu, Hangbo Liu, Kai Sun, Chenxin Geng, Haochen Liu, Hailan Feng, Yang Liu, Hu Zhao, Dong Han   +9 more
wiley   +1 more source

Proneurotrophin-3 contributes to chemotherapy-induced neuropathic pain through TrkC-mediated CCL2 elevation in DRG neurons. [PDF]

EMBO Rep
Sharma D, Feng X, Wang B, Shang H, Yasin B, Bekker A, Hu H, Tao YX.   +7 more
europepmc   +1 more source

Time course of changes in μ-opioid receptor mRNA level by microinjection of antisense oligodeoxynucleotides directed against μ-opioid receptor mRNA into the periaqueductal gray

, 1997
Masanobu Yoshikawa, Kouichi Yokogami, Ken Kitamura, Tomomi Kobayashi, Masayuki Kanal, Takao Taniguchi, Kazuhito Akahon, Kayoko Iwao, Tetsuo Oka   +8 more
openalex   +1 more source