Results 211 to 220 of about 99,497 (338)

Corticotropin‐releasing factor type 1 receptors in the rat nodose ganglion are involved in the transduction of stress‐induced visceral sensory signals to the brain

open access: yesJournal of Neuroendocrinology, EarlyView.
Corticotropin‐releasing factor (CRF) and its type 1 receptor (CRF1) are expressed in the rat colon. The vagal nodose ganglion transmits visceral information to the brain; but whether the CRF/CRF1 system is involved in vagal afferent function remains unknown.
Asuka Mano‐Otagiri   +3 more
wiley   +1 more source

The pharmacotherapeutic potential of neuropeptide Y for chronic pain

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Chronic pain is a major medical problem that requires new therapeutic options. Discovered by Victor Mutt in 1982, neuropeptide Y (NPY) is rapidly emerging as a master regulator of pain relief. Genetic knockdown of NPY or pharmacological inhibition of its receptors demonstrates that NPY signaling tonically inhibits indices of chronic ...
Al A. Nie, Bradley K. Taylor
wiley   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

open access: yesJournal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde   +9 more
wiley   +1 more source

Loss-of-consciousness: sources of GABAergic input to the mesopontine tegmental anesthesia area. [PDF]

open access: yesFront Neurosci
Ibraheem A   +5 more
europepmc   +1 more source

Transformation of constituent cells of tomato callus aggregates by intranuclear microinjection.

open access: bronze, 1989
Hideyoshi Toyoda   +5 more
openalex   +2 more sources

Administration of the Sleep‐Promoting Neuromodulator Adenosine Into the Median Preoptic and Septal Region Produced Thermal Hyperalgesia

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Abundant clinical and preclinical evidence demonstrates that sleep and pain have bidirectional interactions. Sleep loss enhances pain perception and pain disrupts sleep. However, the exact neurobiological mechanisms through which sleep loss alters pain remain poorly understood.
Viviane S. Hambrecht‐Wiedbusch   +5 more
wiley   +1 more source

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