Results 261 to 270 of about 99,497 (338)

Disruption of the actin cytoskeleton after microinjection of proteolytic fragments of alpha-actinin

, 1991
Fredrick M. Pavalko, Keith Burridge
openalex   +2 more sources

Ventral Anterior–Lateral Complex of the Thalamus Mediates Chronic Stress‐Induced Pain Hypersensitivity and Underlies Electroacupuncture Analgesia

Brain and Behavior, Volume 15, Issue 9, September 2025.
Chronic restraint stress (CRS) necessarily and sufficiently induces hyperalgesia by activating ventral anterior–lateral complex of the thalamus (VAL) CaMKIIα‐positive neurons. Electroacupuncture alleviates CRS‐induced paw mechanical allodynia and thermal hyperalgesia by suppressing these VAL neurons.
Jie Chen, Qinling Li, Wei Yu, Min He, Zui Shen, Peipei Feng   +5 more
wiley   +1 more source

Acute Optogenetic Activation of the Subfornical Organ Produces Sympathetically Mediated Increases in Blood Pressure.

Neuroendocrinology
Van Acquoy ML, Nedelkoska T, McMullan S, Burke PGR, Hildreth CM.   +4 more
europepmc   +1 more source

The role of the dorsomedial hypothalamus in the cardiogenic sympathetic reflex in the Sprague Dawley rat. [PDF]

Front Physiol
Zahner MR, Hillard KJ, Chandley MC.
europepmc   +1 more source

Actin Filament Pointed Ends: Assays for Regulation of Assembly and Disassembly by Tropomodulin and Tropomyosin

Cytoskeleton, Volume 82, Issue 9, Page 571-591, September 2025.
ABSTRACT Actin filaments are dynamic polymers whose length depends on regulated monomer association and dissociation at their ends. Actin barbed‐end dynamics are relatively better understood, primarily due to the approximately tenfold faster subunit on/off rates at barbed versus pointed ends.
Sawako Yamashiro, Shashank Shekhar, Stefanie M. Novak, Sudipta Biswas, Carol C. Gregorio, Velia M. Fowler   +5 more
wiley   +1 more source

GABA_B receptor activation contributes to post-surgery cognitive impairments in mice by inducing hippocampal BDNF hypermethylation. [PDF]

Ann Med
Wu T, Sun XY, Cao J, Tong K, Hao JR, Sun N, Gao C.   +6 more
europepmc   +1 more source

Embryo development, pregnancy and twin delivery after microinjection of 'stump' spermatozoa

, 1999
R. J. Favero, Flavio Rizzo, B. Baccetti, Paola Piomboni   +3 more
openalex   +1 more source

Mitochondrial Diseases: Molecular Pathogenesis and Therapeutic Advances

MedComm, Volume 6, Issue 9, September 2025.
Key pathogenic mechanisms—OXPHOS defects, heteroplasmy, impaired mtDNA repair, disrupted dynamics/mitophagy, and inflammatory signaling—drive multiorgan involvement in mitochondrial diseases. Targeted interventions include metabolic drugs (CoQ10, idebenone, EPI‐743), mitochondrial gene editing (DdCBE, mitoBEs, CyDENT/mitoTALEN/mtZFN), and mitochondrial
Jialun Mei, Peng Ding, Chuan Gao, Jian Zhou, Zhiwei Li, Changqing Zhang, Junjie Gao   +6 more
wiley   +1 more source

A Novel PLCζ Mutation Linked to Male Factor Infertility Induces a Gain-of-Function Effect on Ca²⁺ Oscillations in Eggs. [PDF]

Int J Mol Sci
Saleh A, Huang Z, Al Shaikh M, Jurkowski TP, Islam Z, Swann K, Nomikos M.   +6 more
europepmc   +1 more source

Mitochondrial Dysfunction in Aging: Future Therapies and Precision Medicine Approaches

MedComm – Future Medicine, Volume 4, Issue 3, September 2025.
Mitochondria play a critical role in aging and aging‐related diseases. This review systematically explores the mechanisms underlying mitochondrial deterioration during aging and highlights innovative therapeutic strategies for these mitochondrial problems.
Lanlan Jia, Ziyu Wei, Jinyuan Luoqian, Xi Wang, Chao Huang   +4 more
wiley   +1 more source