Results 271 to 280 of about 99,497 (338)

A Low Frequency of Chromosomal Integration of Cloned DNA after Microinjection into the Cytoplasm of Fertilized Eggs of Chickens.

open access: bronze, 1998
Katsutoshi Kino   +7 more
openalex   +2 more sources

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava   +9 more
wiley   +1 more source

Neural circuitry of rapid eye movement sleep homeostasis: Mechanistic insights and pathological implications

open access: yesSleep Research, Volume 2, Issue 3, Page 128-144, September 2025.
Abstract Rapid eye movement (REM) sleep is a unique brain state crucial for emotion, memory, and plasticity. Unlike well‐understood non‐REM (NREM) sleep homeostasis, REM sleep homeostasis remains less clearly defined. This review highlights recent progress in understanding REM sleep homeostasis, focusing on its neurophysiological markers, neural ...
Ting He
wiley   +1 more source

Cytotransducers for Visualization of Spatiotemporal Intercellular Communication

open access: yesSmall, Volume 21, Issue 35, September 4, 2025.
Cytotransducers are constructed to visualize intercellular communication based on the spatiotemporally controlled intervention of nanometer‐sized artifacts as stable tracers. The designed cytotransducer is 110 nm in size and composed of a lipid membrane and fluorescent nanodiamond.
Niko Kimura   +2 more
wiley   +1 more source

Microinjection, gene knockdown, and CRISPR-mediated gene knock-in in the hard coral, Astrangia poculata. [PDF]

open access: yesEvodevo
Warner JF   +6 more
europepmc   +1 more source

GPD1L‐Mediated Glycerophospholipid Metabolism Dysfunction in Women With Diminished Ovarian Reserve: Insights From Pseudotargeted Metabolomic Analysis of Follicular Fluid

open access: yesCell Proliferation, Volume 58, Issue 9, September 2025.
Our study demonstrated the downregulation of GPD1L and its mediated glycerophospholipid metabolism dysfunction in patients with diminished ovarian reserve. Moreover, we verified that GPD1L knockdown leads to increased cell apoptosis and mitochondrial dysfunction of KGN cells, as well as impaired oocyte quality.
Jiaqi Wu   +8 more
wiley   +1 more source

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