Results 71 to 80 of about 99,497 (338)
Antibiotics, 2023 (1) Background: Microinjection of zebrafish (Danio rerio) embryos offers a promising model for studying the virulence and potential environmental risks associated with Pseudomonas aeruginosa. (2) Methods: This work aimed to develop a P.
Edit Kaszab +8 more
doaj +1 more source
Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]
, 2013 Although mutations in the huntingtin gene (HTT) due to poly-Q expansion cause neuropathology in humans (Huntington's disease; HD), the normal function(s) of the gene and its protein (HTT) remain obscure.
Brown, Euan R. +2 more
core +1 more source
Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice
Advanced Science, EarlyView.PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu +8 more
wiley +1 more source
Microfluidic Device for Microinjection of Caenorhabditis elegans
Micromachines, 2020 Microinjection is an established and reliable method to deliver transgenic constructs and other reagents to specific locations in C. elegans worms. Specifically, microinjection of a desired DNA construct into the distal gonad is the most widely used ...
Reza Ghaemi +3 more
doaj +1 more source
Paraventricular Nucleus Modulates Excitatory Cardiovascular Reflexes during Electroacupuncture. [PDF]
, 2016 The paraventricular nucleus (PVN) regulates sympathetic outflow and blood pressure. Somatic afferent stimulation activates neurons in the hypothalamic PVN.
Fu, Liang-Wu +3 more
core +1 more source
Advanced Science, EarlyView.A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen +16 more
wiley +1 more source
Advanced Science, EarlyView.Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu +13 more
wiley +1 more source
DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine self‐administration in rats [PDF]
, 2019 Drug‐reinforced excessive operant responding is one fundamental feature of long-lasting addiction‐like behaviors and relapse in animals. However, the transcriptional regulatory mechanisms responsible for the persistent drug‐specific (not natural rewards)
Duan, Ying +8 more
core +1 more source
A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche
Advanced Science, EarlyView.A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia +14 more
wiley +1 more source
The Role of Nod Factor Substituents in Actin Cytoskeleton Rearrangements in Phaseolus vulgaris
Molecular Plant-Microbe Interactions, 2003 In order to define the symbiotic role of some of the chemical substituents in the Rhizobium etli Nod factors (NFs), we purified Nod metabolites secreted by the SM25 strain, which carries most of the nodulation genes, and SM17 with an insertion in nodS ...
Luis Cárdenas +5 more
doaj +1 more source