Results 271 to 280 of about 36,831 (386)

Rapidly separable microneedle patch for the sustained release of a contraceptive

open access: yesNature Biomedical Engineering, 2019
Wei Li   +5 more
semanticscholar   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

Structural characterisation and transdermal delivery studies on sugar microneedles: Experimental and finite element modelling analyses [PDF]

open access: green, 2014
Eriketi Z. Loizidou   +6 more
openalex   +1 more source

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

open access: yesIbrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li   +10 more
wiley   +1 more source

Hydrogel-Forming Microneedles Increase in Volume During Swelling in Skin, but Skin Barrier Function Recovery is Unaffected [PDF]

open access: green, 2014
Ryan F. Donnelly   +7 more
openalex   +1 more source

Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles

open access: yesInterdisciplinary Materials, EarlyView.
This study explores the dysregulated “mitophagy–apoptosis–inflammation” axis in hypertrophic scar (HS) pathophysiology and proposes a synergistic therapy to restore microenvironmental homeostasis. By targeting mitochondrial dysfunction and inflammatory signaling, the strategy enhances scar regression, providing a novel clinical approach for HS ...
Shengjie Jiang   +11 more
wiley   +1 more source

MXenes‐based flexible electronics for wound monitoring and treatment

open access: yesInterdisciplinary Medicine, EarlyView.
This article provides a comprehensive overview of recent advancements in MXenes‐based flexible electronic devices for wound monitoring. It discusses the monitoring mechanisms and values for various wound pathological parameters as well as their applications in treating bacterial infections and chronic wounds.
Ye Yang   +6 more
wiley   +1 more source

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