Results 131 to 140 of about 9,159 (257)

Dissolving Microneedles Loaded with Lipid Nanocarriers for Vaginal Delivery of Clotrimazole: <i>In Vitro</i> and <i>Ex Vivo</i> Evaluation. [PDF]

Mol Pharm
Udayakumar P, Škalko-Basnet N, Rondahl V, Cotaquispe CFS, Hemmingsen LM, Sotiriou GA, Du J, Teleki A.   +7 more
europepmc   +1 more source

Machine Learning‐Guided Near‐Infrared Laser Processing for Precise Geometry Control in Microneedles with Downstream microLED‐Triggered Photothermal Functionality

Small, EarlyView.
Machine learning‐guided near‐infrared laser processing enables predictive fabrication of microneedles with application‐specific geometries. The optimized metal templates are translated into polymeric microneedles and integrated with a flexible microLED platform.
Ismail Eş, Burak M. Gormus, Pinar Ayas, Irfan Ullah, Christopher M. Proctor   +4 more
wiley   +1 more source

Advances in microneedle design for the delivery of drugs, proteins, and cells in the treatment of hypertrophic scars. [PDF]

Burns Trauma
Guo J, Tang Q, Ge Z, Xia Q, Liu H, Shi H, Huang J, Chen J, Cooper MS, Yan X, Yang C, Wang Y.   +11 more
europepmc   +1 more source

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

Small, EarlyView.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

Highly cited original research in microneedle science from 2015 to 2025 a bibliometric and altmetric analysis. [PDF]

Discov Nano
Chen X, Zhang Q, Zhao C, Wang G, Ren H, Yang M, Liu S, Liu T, Guo B.   +8 more
europepmc   +1 more source

Immunomodulatory Nanozymes as Programmable Redox–Immune Set‐Point Regulators

Small, EarlyView.
Conceptual phase space linking reactive oxygen species level/dynamics to immune state, with pathological set‐points for chronic inflammation, tumor escape, and degeneration contrasted against a central healthy redox–immune set‐point. Buffering and amplifying nanozymes are depicted as devices that dial redox tone up or down to steer diseased ...
Sumi Choi, Minjeong Kim, Sang Jin Lee, Su‐Hwan Kim   +3 more
wiley   +1 more source

Advanced Sensing and Delivery Technologies for Nose-to-Brain Administration: From Nanocarriers to Sensor-Integrated Organ-on-Chips. [PDF]

Sensors (Basel)
Liu X, Chen R, Wu F, Yu B, Zhou G, Hu S, Zhang H, Wang P, Xu B, Zhuang L.   +9 more
europepmc   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

A sequential defense-nourishment strategy enabled by thermosensitive core-shell microneedles for synergistic tendon repair. [PDF]

Mater Today Bio
Fu M, Li J, Jiang Y, Shao Y, Wu D, Zhong S, Huang Z, Chen C, Guo J, Xie D, Zeng C.   +10 more
europepmc   +1 more source

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source