Results 311 to 320 of about 33,747 (400)

Development of a Novel Transdermal Delivery System of Alendronate, a Nitrogen Containing Bisphosphonate, Using a New Type of Hydrophilic Patch and Dissolving Microneedle Arrays

, 2014
Hidemasa Katsumi
openalex   +2 more sources

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Chitosan-Based Intelligent Microneedles for Delivery of Amphotericin B Loaded Oleosomes: Antifungal Ocular Patch Targeting for Effective Against Fungal Keratitis Using Rabbit Model via TLR4/NLRP3 Pathway. [PDF]

Int J Nanomedicine
Elhabal SF, Al-Zuhairy SAS, Elrefai MFM, El-Nabarawi MA, Hababeh S, Zarif Attalla K, Shoela MS, Nelson J, Fady M, Elzohairy NA, Amin ME, Ahmed HS, Ewedah TM, Mousa I, Hamdan AME.   +14 more
europepmc   +1 more source

Laser-engineered dissolving microneedle arrays for protein delivery: potential for enhanced intradermal vaccination

, 2014
Maelíosa McCrudden, Barbara M. Torrisi, Sharifah Al-Zahrani, Cian M. McCrudden, Marija Zaric, Christopher J. Scott, Adrien Kissenpfennig, Helen O. McCarthy, Ryan F. Donnelly   +8 more
openalex   +2 more sources

Fabrication of Microneedles by Pulsating In Situ Dried Electrostretching for Transdermal Drug Delivery

Small Methods, EarlyView.
The pulsating in situ dried electrostretching (PIDES) technique offers a novel approach to microneedles fabrication for transdermal drug delivery utilizing electrohydrodynamic principles. PIDES is capable of fabricating biodegradable polymeric microneedles with geometric and mechanical properties suitable for skin penetration. Drug loading and in vitro
Ngoc Luan Mai, Yuen Yong, Thi Van Anh Hoang, Trung Hieu Vu, Hoai‐Duc Vu, Van Canh Doan, Donglin Cai, Thien Xuan Dinh, Dzung Viet Dao, Van Thanh Dau   +9 more
wiley   +1 more source

Microneedles in diabetic wound care: multifunctional solutions for enhanced healing. [PDF]

Burns Trauma
Jian X, Deng Y, Xiao S, Qi F, Deng C.
europepmc   +1 more source

DNA vaccination via polymeric microneedles; the use of a novel amphipathic peptide [PDF]

, 2013
Helen O. McCarthy, Joanne McCaffrey, Cian M. McCrudden, Ryan F. Donnelly   +3 more
openalex  

A Smart Functional Microneedle, Tethered with Neuropeptide S and Tissue Inhibitor of Metalloproteinases, Promotes Skin, Vascular, and Nerve Regeneration for Chronic Diabetic Skin Wound Healing

Small Structures, EarlyView.
A smart functional microneedle system, tethered with NPS and TIMP, which not only promotes diabetic wound healing and tissue remodeling at the injury site but also demonstrates the ability to dynamically and responsively release NPS and TIMP as needed, offering a potential therapeutic approach for clinical translation is presented. Increased expression
Yan Gao, Mengdan Cheng, Yiqing Wu, Liangliang Zhang, Bai Xu, Xiaojie Lu   +5 more
wiley   +1 more source

Unique advantages and applications of polysaccharide microneedles as drug delivery materials and in treatment of skin diseases. [PDF]

Nanoscale Adv
Liu C, Liu M, Li X, Hu Y, Zhang L, You FM, Fan G, Ge Y.   +7 more
europepmc   +1 more source

A paper‐based bi‐enzymatic sensor for chemiresistive glucose detection

VIEW, EarlyView.
This paper presents the development of a paper‐based glucose sensor utilizing poly(3,4‐ethylene‐dioxythiophene) polystyrene sulfonate (PEDOT:PSS) and a bi‐enzymatic system with Horseradish Peroxidase (HRP) and Glucose Oxidase (GOx). The chemiresistive sensor is optimized for detecting glucose in biofluids such as saliva, requiring only 40 µL of sample ...
Riccardo Zulli, Jacopo Giaretta, Theja Prabhakar, Ronil J Rath, Suvan Shrestha, Sara Spilimbergo, Syamak Farajikhah, Fariba Dehghani   +7 more
wiley   +1 more source