Results 1 to 10 of about 127 (70)

PyDapsys: an open-source library for accessing electrophysiology data recorded with DAPSYS

Frontiers in Neuroinformatics, 2023
In the field of neuroscience, a considerable number of commercial data acquisition and processing solutions rely on proprietary formats for data storage.
Peter Konradi, Alina Troglio, Ariadna Pérez Garriga, Aarón Pérez Martín, Rainer Röhrig, Barbara Namer, Barbara Namer, Barbara Namer, Ekaterina Kutafina   +8 more
doaj   +1 more source

Cardiovascular reflex contributions to sympathetic inhibition during low intensity dynamic leg exercise in healthy middle‐age

Physiological Reports, 2023
Aging augments resting muscle sympathetic nerve activity (MSNA) and sympatho‐inhibition during mild dynamic 1‐leg exercise. To elucidate which reflexes elicit exercise‐induced inhibition, we recruited 19 (9 men) healthy volunteers (mean age 56 ± 9 SD ...
Catherine F. Notarius, Mark B. Badrov, Tomoyuki Tobushi, Daniel A. Keir, Evan Keys, John S. Floras   +5 more
doaj   +1 more source

Decoding Neuropathic Pain: Can We Predict Fluctuations of Propagation Speed in Stimulated Peripheral Nerve?

Frontiers in Computational Neuroscience, 2022
To understand neural encoding of neuropathic pain, evoked and resting activity of peripheral human C-fibers are studied via microneurography experiments.
Ekaterina Kutafina, Ekaterina Kutafina, Alina Troglio, Roberto de Col, Roberto de Col, Rainer Röhrig, Peter Rossmanith, Barbara Namer, Barbara Namer   +8 more
doaj   +1 more source

Limited evidence for sympathetic neural overactivation in older patients with type 2 diabetes mellitus

Frontiers in Neuroscience, 2023
IntroductionMechanistic studies suggested that excess sympathetic activity promotes arterial hypertension while worsening insulin sensitivity. Older patients with type 2 diabetes are at particularly high cardiovascular and metabolic risk.
Karsten Heusser, Jens Tank, André Diedrich, André Diedrich, Annelie Fischer, Tim Heise, Jens Jordan, Jens Jordan   +7 more
doaj   +1 more source

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

BioMedical Engineering OnLine, 2019
Background The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the processing of descending efferent neural signals recorded using peripheral neural interfaces
Francesco M. Petrini, Alberto Mazzoni, Jacopo Rigosa, Federica Giambattistelli, Giuseppe Granata, Beatrice Barra, Alessandra Pampaloni, Eugenio Guglielmelli, Loredana Zollo, Marco Capogrosso, Silvestro Micera, Stanisa Raspopovic   +11 more
doaj   +1 more source

Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors

EBioMedicine, 2019
Background: Small fiber neuropathy (SFN) is a severe and disabling chronic pain syndrome with no causal and limited symptomatic treatment options. Mechanistically based individual treatment is not available. We report an in-vitro predicted individualized
Barbara Namer, Diana Schmidt, Esther Eberhardt, Michele Maroni, Eva Dorfmeister, Inge Petter Kleggetveit, Luisa Kaluza, Jannis Meents, Aaron Gerlach, Zhixin Lin, Andreas Winterpacht, Elena Dragicevic, Zacharias Kohl, Jürgen Schüttler, Ingo Kurth, Torhild Warncke, Ellen Jorum, Beate Winner, Angelika Lampert   +18 more
doaj   +1 more source

A modelling study to dissect the potential role of voltage-gated ion channels in activity-dependent conduction velocity changes as identified in small fiber neuropathy patients

Frontiers in Computational Neuroscience, 2023
ObjectivePatients with small fiber neuropathy (SFN) suffer from neuropathic pain, which is still a therapeutic problem. Changed activation patterns of mechano-insensitive peripheral nerve fibers (CMi) could cause neuropathic pain.
Anna Maxion, Ekaterina Kutafina, Maike F. Dohrn, Pierre Sacré, Angelika Lampert, Jenny Tigerholm, Barbara Namer, Barbara Namer, Barbara Namer   +8 more
doaj   +1 more source

Firing patterns of muscle vasoconstrictor neurones in respiratory disease

Frontiers in Physiology, 2012
Because the cardiovascular system and respiration are so intimately coupled, disturbances in respiratory control often lead to disturbances in cardiovascular control.
Vaughan G Macefield
doaj   +1 more source

Mapping quantal touch using 7 Tesla functional magnetic resonance imaging and single-unit intraneural microstimulation

eLife, 2016
Using ultra-high field 7 Tesla (7T) functional magnetic resonance imaging (fMRI), we map the cortical and perceptual responses elicited by intraneural microstimulation (INMS) of single mechanoreceptive afferent units in the median nerve, in humans ...
Rosa Maria Sanchez Panchuelo, Rochelle Ackerley, Paul M Glover, Richard W Bowtell, Johan Wessberg, Susan T Francis, Francis McGlone   +6 more
doaj   +1 more source

Autonomic markers of emotional processing: skin sympathetic nerve activity in humans during exposure to emotionally-charged images

Frontiers in Physiology, 2012
The sympathetic innervation of the skin primarily subserves thermoregulation, but the system has also been commandeered as a means of expressing emotion.
Rachael eBrown, Rachael eBrown, Cheree eJames, Luke eHenderson, Vaughan G Macefield, Vaughan G Macefield   +5 more
doaj   +1 more source