Results 141 to 150 of about 19,552 (165)

Mechanical stress during confined migration causes aberrant mitoses and c-MYC amplification. [PDF]

Proc Natl Acad Sci U S A
Bastianello G, Kidiyoor GR, Lowndes C, Li Q, Bonnal R, Godwin J, Iannelli F, Drufuca L, Bason R, Orsenigo F, Parazzoli D, Pavani M, Cancila V, Piccolo S, Scita G, Ciliberto A, Tripodo C, Pagani M, Foiani M.   +18 more
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Genome instability and crosstalk with the immune response. [PDF]

Genome Med
Chabanon RM, Danlos FX, Ouali K, Postel-Vinay S.   +3 more
europepmc   +1 more source

Microtubule poleward flux as a target for modifying chromosome segregation errors. [PDF]

Proc Natl Acad Sci U S A
Risteski P, Martinčić J, Jagrić M, Tintor E, Petelinec A, Tolić IM.   +5 more
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DNA2 enables growth by restricting recombination-restarted replication. [PDF]

Nature
Hudson JJR, Appanah R, Jones D, Davidson K, Budden AM, Vaitsiankova A, Chan KL, Caldecott KW, Carr AM, Rass U.   +9 more
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Primary cilia function as hubs for signal transduction. [PDF]

Cell Biosci
Li B, He YY, Yang ZM.
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Chromosome aberrations cause tumorigenesis through chromosomal rearrangements in a hepatocarcinogenesis rat model. [PDF]

Cancer Sci
Nakamura K, Ishii Y, Takasu S, Namiki M, Soma M, Takimoto N, Matsushita K, Shibutani M, Ogawa K.   +8 more
europepmc   +1 more source

β-TrCP-Mediated Proteolysis of Mis18β Prevents Mislocalization of CENP-A and Chromosomal Instability. [PDF]

Mol Cell Biol
Sethi SC, Shrestha RL, Balachandra V, Durairaj G, Au WC, Nirula M, Karpova TS, Kaiser P, Basrai MA.   +8 more
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Nuclear mechanostability emerges from satellite DNA condensation into chromocenters

Brändle FB, Frühbauer B, Ceppi I, de Monchaux-Irons L, van Heesch T, Sommer A, Rivetti F, Lee SS, Morelli C, Arosio P, Sintsova A, Michaels TC, Cejka P, Vreede J, Jagannathan M.   +14 more
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CHAPTER 2. Mechanisms by Which Genotoxins Cause Micronuclei and Other Nuclear Anomalies

Issues in Toxicology, 2019
Normal eukaryotic cells contain a single nucleus. However, abnormal small nuclei known as micronuclei, additional to the main nucleus, may occur in cells that are exposed to genotoxic agents (chemicals and/or radiation) that cause structural or numerical
M. Fenech
semanticscholar   +1 more source

Micronuclear collapse mechanisms in cancer

Science
Oxidative damage triggers micronuclear membrane rupture and defective repair Errors in chromosome segregation during cell division (mitosis) can lead to chromosomal instability, a hallmark of human cancer.
Marianna Maddaluno, C. Settembre
semanticscholar   +1 more source