Results 71 to 80 of about 21,961 (167)

Microsporogenesis in Brachiaria brizantha (Poaceae) as a selection tool for breeding. [PDF]

, 2018
The genus Brachiaria comprises more than 100 species and is the single most important genus of forage grass in the tropics. Brachiaria brizantha , widely used in Brazilian pastures for beef and dairy production, is native to tropical Africa. As a subsidy
BERNARDO, Z. H., CALISTO, V., MENDES, D. V., MENDES-BONATO, A. B., PAGLIARINI, M. S., SANTOS, E. M., SILVA, N., VALLE, C. B. do   +7 more
core  

cTAGE5/MEA6 Regulates LBR Localization to Maintain Nuclear Envelope Integrity and Safeguard Against Aging

Aging Cell, Volume 24, Issue 10, October 2025.
cTAGE5 regulates LBR trafficking between the ER and the nucleus membrane to maintain the integrity of both the ER and the nuclear envelope. cTAGE5 KO results in LBR retention in the ER, reduced stability, and subsequent disruption of nuclear envelope integrity. ABSTRACT cTAGE5/MEA6 plays a pivotal role in COPII complex assembly, ER‐to‐Golgi trafficking,
Yaqing Wang, Pengyu Sun, Fuqiang Yang, Tiantian Ma, Junwan Fan, Lei Shi, Nan Li, Fei Gao, Kangmin He, Zhiheng Xu   +9 more
wiley   +1 more source

TRAIP regulates replication fork recovery and progression via PCNA [PDF]

, 2016
published_or_final_versio
Deng, Y, Feng, W, Guo, Y, Huang, J, Huen, MSY, Zang, J   +5 more
core   +1 more source

Mitosis-specific phosphorylation of Mis18α by Aurora B kinase enhances kinetochore recruitment of polo-like kinase 1

OncoTarget, 2017
Mis18α, a component of Mis18 complex comprising of Mis18α, Mis18β, and M18BP1, is known to localize at the centromere from late telophase to early G1 phase and plays a priming role in CENP-A deposition.
Minkyoung Lee, Ik Soo Kim, Koog Chan Park, Jong-Seo Kim, S. H. Baek, Keun-Il Kim   +5 more
semanticscholar   +1 more source

Approaches to repurposing reverse transcriptase antivirals in cancer

British Journal of Clinical Pharmacology, Volume 91, Issue 9, Page 2494-2506, September 2025.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head, Saiful Islam, Jennifer H. Martin   +2 more
wiley   +1 more source

The Interplay of Aging and Cancer: Mechanisms, Implications, and Therapeutic Strategies

MedComm – Oncology, Volume 4, Issue 3, September 2025.
Aging and cancer form a vicious cycle: aging alters the tumor microenvironment, promotes senescence, and reshapes cancer progression and therapy response. In return, cancer and its treatments accelerate aging through inflammation and genomic damage. Novel strategies‐senolytics, CAR‐T, and artificial intelligence‐offer exciting opportunities to disrupt ...
Liangce Wang, Yaru Luo, Xin Chen, Yuan Wang, Yan Zhang   +4 more
wiley   +1 more source

Mussel eggs as indicators of mutagen exposure in coastal and estuarine environments [PDF]

, 1994
The aim of this study was to develop a short-term genotoxicity assay for monitoring the marine environment for mutagens. Based on the developing eggs and embryos of the marine mussel Mytilus edulis, an important pollution indicator species, the test ...
Dixon, D.R., Pascoe, P.L
core  

A p62-dependent rheostat dictates micronuclei catastrophe and chromosome rearrangements. [PDF]

Science
Chromosomal instability (CIN) generates micronuclei—aberrant extranuclear structures that catalyze the acquisition of complex chromosomal rearrangements present in cancer.
Martin S, Scorzoni S, Cordone S, Mazzagatti A, Beznoussenko GV, Gunn AL, Di Bona M, Eliezer Y, Leor G, Ben-Yishay T, Loffreda A, Cancila V, Rainone MC, Ippolito MR, Martis V, Bedin F, Garrè M, Vaites LP, Vasapolli P, Polo S, Parazzoli D, Tripodo C, Mironov AA, Cuomo A, Ben-David U, Bakhoum SF, Hatch EM, Ly P, Santaguida S.   +28 more
europepmc   +2 more sources

Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis [PDF]

, 2017
TREX2 is a 3'-DNA exonuclease specifically expressed in keratinocytes. Here, we investigated the relevance and mechanisms of TREX2 in ultraviolet (UV)-induced skin carcinogenesis. TREX2 expression was up-regulated by chronic UV exposure whereas it was de-
Benito, Carmen, Cañas, Xavier, Eckhart, Leopold, Fischer, Heinz, Forcales Fernàndez, Sonia-Vanina, Garcia-Pedrero, Juana M., Gómez Fernández, Diana Lucía, Manils Pacheco, Joan, Marruecos, Laura, Marzo, Elena, Perrino, Fred W., Rodrigo, Juan P., Salgado, Rocío, Salla i Martret, Mercè, Serafin, Anna M., Serrano, Inma, Soler Prat, Concepció, Toll Abelló, Agustí   +17 more
core   +1 more source

Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition. [PDF]

, 2015
Cellular senescence is a widespread stress response and is widely considered to be an alternative cancer therapeutic goal. Unlike apoptosis, senescence is composed of a diverse set of subphenotypes, depending on which of its associated effector programs ...
Acosta JC, Acosta JC, Allan JA, Andrew R. J. Young, Bain J, Barascu A, Bemiller PM, Bischof O, Bischof O, Cairney CJ, Campisi J, Carmena M, Chandra T, Chang BD, Chang BD, Christian Dillon, Christopher J. Torrance, Chuprin A, Claire J. Cairney, Coppé JP, Correia-Melo C, Cristofalo VJ, Davoli T, Davoli T, Dimri GP, Ditchfield C, Dorothy C. Bennett, Dreesen O, Dörr JR, Ermis A, Ewald JA, Ewald JA, Ferbeyre G, Fujiwara T, Funayama R, Ganem NJ, Ganem NJ, Gascoigne KE, Gautschi O, Gentric G, Gewirtz DA., Gil J, Girdler F, Gizatullin F, Goldenson B, Goldstein S, Green MR, Gully CP, Hardwicke MA, Hauf S, Hayashi MT, Huck JJ, Jackson JG, Jacobs JJ, Johmura Y, Jun JI, Jung JE, Kaestner P, Kang TW, Keen N, Keen N, Kelly AE, Kim HJ, Kirschner K, Kortlever RM, Krenning L, Krizhanovsky V, Kuilman T, Lahtela J, Lauren S. Godwin, Leal JFM, Lens SMA, Li W, Liu Y, López-Otín C, Macleod KF, Maeshima K, Mahito Sadaie, Margolis RL, Masashi Narita, Masashi Narita, Matsumura T, Mitsui Y, Muñoz-Espín D, Narita M, Narita M, Pearson M, Poele te RH, Pérez-Mancera PA, Robert D. Goldman, Rovillain E, Sadaie M, Salama R, Schmitt CA, Serrano M, Shah PP, Shay JW, Shay JW, Shimi T, Shvarts A, Silva JM, Storchova Z, Storer M, Uetake Y, Vitale I, W. Nicol Keith, Wesierska-Gadek J, Wilkinson RW, Wong C, Xue W, Yang J, Young ARJ, Yun M, Zhang R   +113 more
core   +4 more sources