Results 161 to 170 of about 225,804 (391)

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement   +12 more
wiley   +1 more source

Microparticles as Potential Biomarkers of Cardiovascular Disease

open access: yesArquivos Brasileiros de Cardiologia, 2015
Primary prevention of cardiovascular disease is a choice of great relevance because of its impact on health. Some biomarkers, such as microparticles derived from different cell populations, have been considered useful in the assessment of cardiovascular ...
Carolina Nunes França   +4 more
doaj   +1 more source

Microparticle assembly [PDF]

open access: yes, 2015
A bead construct includes a bead, a fluorophore molecule, first and second linker molecules and a ligand molecule. The fluorophore molecule comprises at least two subunits connected to each other by at least one internal linker that provides conformational freedom to the at least two subunits.
Trau, Dieter   +2 more
openaire  

Bioerodable PLGA-Based Microparticles for Producing Sustained-Release Drug Formulations and Strategies for Improving Drug Loading

open access: yesFrontiers in Pharmacology, 2016
Poly(lactic-co-glycolic acid) (PLGA) is the most widely used biomaterial for microencapsulation and prolonged delivery of therapeutic drugs, proteins and antigens.
Felicity Y. Han   +3 more
semanticscholar   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach   +7 more
wiley   +1 more source

Detachment of microparticles from electrode erosion and the subsequent breakdown

open access: yesAIP Advances, 2019
Resulted from electrode erosion, microparticles is common and inevitable in gas switches. Once these microparticles acquire field-induced charge and flee into the gap, there micro-discharge, impact damage and field distortion may occur, which eventually ...
Wei Zhong, Guoliang Zhang, Ao Xu
doaj   +1 more source

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

open access: yesAdvanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam   +5 more
wiley   +1 more source

Gravity compensation in complex plasmas by application of a temperature gradient

open access: yes, 2002
Micron sized particles are suspended or even lifted up in a gas by thermophoresis. This allows the study of many processes occurring in strongly coupled complex plasmas at the kinetic level in a relatively stress-free environment.
C. Gerthsen   +12 more
core   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

open access: yesAdvanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier   +10 more
wiley   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

open access: yesAdvanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy