Results 101 to 110 of about 8,793 (229)
Digital Polymerase Chain Reaction in an Array of Femtoliter Polydimethylsiloxane Microreactors
, 2016 We developed a simple, compact microfluidic device to perform high dynamic-range digital polymerase chain reaction (dPCR) in an array of isolated 36-femtoliter microreactors. The density of the microreactors exceeded 20 000/mm2.
Zitian Chen (2083564) +5 more
core +1 more source
Small, EarlyView.Ultra‐short peptides with a minimal sticker‐spacer structure undergo liquid‐liquid phase separation, resulting in condensates with microenvironments controlled by the hydrophobicity of the spacers. The condensates provide an easily tunable and exceptionally stable scaffold for photocatalytic microreactors in aqueous media, where catalysis efficiency is
Samuel Hamroff, Lucas Caire da Silva
wiley +1 more source
Small, EarlyView.Protein‐based multilayer microreactors combine single‐enzyme nanogels (SENs) and layer‐by‐layer (LbL) assembly to control catalase localization. Positioning the enzyme within the core or at different locations of the multilayer architecture reveals how spatial organization influences antioxidant and anti‐inflammatory activity.
Maria A. Motta +5 more
wiley +1 more source
Smart Molecules, EarlyView.MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag +6 more
wiley +1 more source
Small Methods, EarlyView.Combining synthetic cells engineering, cell‐free expression, and optical regulation may enable a new generation of programmable synthetic cell platforms. By providing spatiotemporal control over biomolecule synthesis, activation, transport, release, and communication, light offers a versatile strategy for coordinating proteins, RNAs, peptides, and ...
Gia Bao Leon Hoang, Taniya Chakraborty
wiley +1 more source
Rapid Flow Synthesis of Zr‐MOF Nanoparticles in Supercritical CO2 for Toxic Chemical Removal
Small Methods, EarlyView.Supercritical CO2 continuous‐flow synthesis produces highly crystalline Zr‐MOFs with residence times as short as 75 s. The resulting UiO‐66 and UiO‐66‐NH2 exhibit high porosity and effective adsorption and degradation of toxic chemicals. ABSTRACT Zirconium‐based metal‐organic frameworks (Zr‐MOFs) are promising materials for the adsorption and ...
Almond Lau +4 more
wiley +1 more source
Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds
The Chemical Record, EarlyView.This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá +4 more
wiley +1 more source
The 5T Paradox of Triclosan: From Toiletries to Toxic Trash, a Growing Threat to Humanity
Environmental Toxicology, EarlyView.ABSTRACT Triclosan (TCS) persists as a contaminant of concern in the Anthropocene, despite regulatory actions. Environmental dissemination continues through wastewater effluents, biosolid application, and improper disposal practices. This narrative review synthesizes current evidence regarding triclosan's environmental fate, transformation pathways ...
Temitope Aribigbola +10 more
wiley +1 more source
Development of continuous processes for vegetable oil alcoholysis in microfluidic devices
Oléagineux, Corps gras, Lipides, 2013 Biodiesel can be produced from vegetable oils, animal fats, and waste cooking oils by transesterification with ethanol (also called ethanolysis) in order to substitute fossil fuels.
Richard Romain +3 more
doaj +1 more source
Compartmentalisation in cAMP signalling: A phase separation perspective
British Journal of Pharmacology, EarlyView.Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley +1 more source