Results 11 to 20 of about 3,389 (175)

In Vivo Evaluation of Efficacy and Toxicity of Bioinspired Peptides With Antimicrobial Properties Against Fungal Infection in Galleria mellonella Larvae

open access: yesInternational Journal of Microbiology
Background Fungal infections, particularly those caused by Candida species, represent a growing public health threat due to increasing resistance to conventional antifungal agents. Consequently, there is a need for the development of novel antifungals. Objective This study evaluated the in vivo toxicity and efficacy of three peptides with antimicrobial
Allan da Silva Conceição   +4 more
doaj   +2 more sources

SdiA, a Quorum-Sensing Regulator, Suppresses Fimbriae Expression, Biofilm Formation, and Quorum-Sensing Signaling Molecules Production in Klebsiella pneumoniae

open access: yesFrontiers in Microbiology, 2021
Klebsiella pneumoniae is a Gram-negative pathogen that has become a worldwide concern due to the emergence of multidrug-resistant isolates responsible for various invasive infectious diseases. Biofilm formation constitutes a major virulence factor for K.
Thaisy Pacheco   +6 more
doaj   +1 more source

Functional Insights From KpfR, a New Transcriptional Regulator of Fimbrial Expression That Is Crucial for Klebsiella pneumoniae Pathogenicity

open access: yesFrontiers in Microbiology, 2021
Although originally known as an opportunistic pathogen, Klebsiella pneumoniae has been considered a worldwide health threat nowadays due to the emergence of hypervirulent and antibiotic-resistant strains capable of causing severe infections not only on ...
Ana Érika Inácio Gomes   +6 more
doaj   +1 more source

Influence of the Polysaccharide Capsule on the Bactericidal Activity of Indolicidin on Streptococcus pneumoniae

open access: yesFrontiers in Microbiology, 2022
Streptococcus pneumoniae is a pathogen responsible for high morbidity and mortality worldwide. The polysaccharide capsule confers protection against phagocytosis and influences many aspects of pneumococcal pathogenesis. The capsular polysaccharides (CPS)
Natalha T. Waz   +8 more
doaj   +1 more source

Evaluation of hypochlorous acid as an ear flush in dogs with chronic otitis externa

open access: yesVeterinary Dermatology, Volume 34, Issue 2, Page 134-141, April 2023., 2023
Abstract Background Chronic otitis externa (OE) in dogs frequently requires anaesthetised ear flushing. Objectives To evaluate hypochlorous acid as an ear flushing and antimicrobial agent in dogs with chronic OE. Animals Twenty dogs with chronic OE caused by the same organisms bilaterally.
Ralf S. Mueller   +5 more
wiley   +1 more source

A plasmid network from the gut microbiome of semi-isolated human groups reveals unique and shared metabolic and virulence traits

open access: yesScientific Reports, 2022
The plasmids in gut microbiomes have the potential to contribute to the microbiome community, as well as human health and physiology. Nevertheless, this niche remains poorly explored.
Liliane Costa Conteville   +1 more
doaj   +1 more source

Whole genome sequencing and de novo assembly of Staphylococcus pseudintermedius: a pangenome approach to unravelling pathogenesis of canine pyoderma

open access: yesVeterinary Dermatology, Volume 32, Issue 6, Page 654-663, December 2021., 2021
Background Staphylococcus pseudintermedius is the main aetiological agent of canine pyoderma. Whole genome sequencing is the most comprehensive way of obtaining relevant genomic information about micro‐organisms. Hypothesis/Objectives Oxford Nanopore technology enables quality sequencing and de novo assembly of the whole genome of S.
Lluís Ferrer   +13 more
wiley   +1 more source

Molecular Detection of Drug-Resistance Genes of blaOXA-23-blaOXA-51 and mcr-1 in Clinical Isolates of Pseudomonas aeruginosa

open access: yesMicroorganisms, 2021
Pseudomonas aeruginosa has caused high rates of mortality due to the appearance of strains with multidrug resistance (MDR) profiles. This study aimed to characterize the molecular profile of virulence and resistance genes in 99 isolates of P.
Fabiana Nitz   +12 more
doaj   +1 more source

Gardnerella vaginalis and Neisseria gonorrhoeae Are Effectively Inhibited by Lactobacilli with Probiotic Properties Isolated from Brazilian Cupuaçu (Theobroma grandiflorum) Fruit

open access: yesBioMed Research International, Volume 2021, Issue 1, 2021., 2021
In recent years, certain Lactobacillus sp. have emerged in health care as an alternative therapy for various diseases. Based on this, this study is aimed at evaluating in vitro the potential probiotics of five lactobacilli strains isolated from pulp of cupuaçu fruit fermentation against Gardnerella vaginalis and Neisseria gonorrhoeae.
Nathan das Neves Selis   +20 more
wiley   +1 more source

Diclofenac May Induce PIA‐Independent Biofilm Formation in Staphylococcus aureus Strains

open access: yesInternational Journal of Microbiology, Volume 2021, Issue 1, 2021., 2021
Staphylococcus aureus is a pathogen commonly resistant to antibiotics. Biofilm formation is one of the important factors related to its virulence. Non‐antibiotics drugs, such as nonsteroidal anti‐inflammatory agents (NSAIDs), have been studied as an alternative for treating infections by multiresistant pathogens and biofilm‐associated infections.
Agostinho Alves de Lima e Silva   +7 more
wiley   +1 more source

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