Results 271 to 280 of about 661,223 (352)

A microRNA component of the p53 tumour suppressor network

open access: yesNature, 2007
Lin He   +15 more
semanticscholar   +1 more source

RNA‐Lebendzellmikroskopie via click‐funktionalisierter TriPPPro Nucleotid‐Reporter

open access: yesAngewandte Chemie, EarlyView.
Die intrazelluläre Zufuhr von trans‐Cycloocten und Bicyclo[6.1.0]nonin als sterisch anspruchsvolle Gruppen für die Diels–Alder‐Reaktion mit inversem Elektronenbedarf wurde durch die Triphosphat‐Prodrug‐Strategie (TriPPPro) erreicht. Nach der Hydrolyse innerhalb der Zelle werden die modifizierten Uridine und Cytidine metabolisch in die neu entstehende ...
J. Iven H. Knaack   +6 more
wiley   +1 more source

Live‐Cell RNA Imaging via Clickable TriPPPro Nucleotide Reporters

open access: yesAngewandte Chemie International Edition, EarlyView.
The intracellular delivery of trans‐cyclooctene and bicyclo[6.1.0]nonyne as sterically demanding groups for the inverse electron‐demand Diels–Alder was achieved by the triphosphate prodrug (TriPPPro) strategy. Once hydrolyzed inside cells, the modified uridines and cytidines are metabolically incorporated into nascent RNA, are labelled by a dual ...
J. Iven H. Knaack   +6 more
wiley   +1 more source

Oligonucleotide surface attachment by tosylation for digital detection of microRNA using photonic resonator absorption microscopy. [PDF]

open access: yesAPL Bioeng
Shepherd S   +9 more
europepmc   +1 more source

MicroRNA biogenesis pathways in cancer

open access: yesNature Reviews. Cancer, 2015
Shuibin Lin, R. Gregory
semanticscholar   +1 more source

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

open access: yesAnimal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary   +7 more
wiley   +1 more source

A symphony of signals: the intricate role of lncRNAs in dermatological disorders. [PDF]

open access: yesClin Exp Med
Vanan AG   +6 more
europepmc   +1 more source

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