Results 321 to 330 of about 497,158 (357)

microRNA Decay: Refining microRNA Regulatory Activity

MicroRNA, 2017
MicroRNAs (miRNAs) are short 19-25 nucleotide RNA molecules that impact on most biological processes by regulating the efficiency of messenger RNA (mRNA) translation. To date, most research activities have been focused on the control of miRNA expression and its functional consequences.
Genevieve, Pepin, Michael P, Gantier
openaire   +2 more sources

The MicroRNA

2012
MicroRNAs (miRNAs), widely distributed, small regulatory RNA genes, target both messenger RNA (mRNA) degradation and suppression of protein translation based on sequence complementarity between the miRNA and its targeted mRNA. Different names have been used to describe various types of miRNA. During evolution, RNA retroviruses or transgenes invaded the
Shao-Yao, Ying, Donald C, Chang, Shi-Lung, Lin   +2 more
openaire   +3 more sources

Participation of microRNAs in human interactome: extraction of microRNA–microRNA regulations

Molecular BioSystems, 2011
To date, a significant amount of research has been conducted for computational modeling of the microRNA (miRNA)-target gene interactions and inferring different kinds of biologically relevant association from their variable expressions, available from microarray experiments.
Debarka, Sengupta, Sanghamitra, Bandyopadhyay   +1 more
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RARs and MicroRNAs

2014
MicroRNA MicroRNA s (miRNAs) are small noncoding RNAs acting as endogenous regulators of gene expression. Their discovery is one of the major recent breakthroughs in molecular biology. miRNAs establish a multiplicity of relationships with target mRNAs and exert pleiotropic biological effects in many cell physiological pathways during development and ...
Nervi, Clara, GRIGNANI, Francesco
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Evolution of MicroRNAs

2006
MicroRNAs (miRNAs) form a large class of small regulatory RNAs in eukaryotes. Although they share a common processing pathway and certain structural features, in general, there is no detectable sequence similarity among miRNAs from a given organism. On the other hand, many miRNAs are members of a family of a few, often very similar, paralogs.
Tanzer, Andrea, Stadler, Peter F
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Viral MicroRNAs, Host MicroRNAs Regulating Viruses, and Bacterial MicroRNA-Like RNAs

2017
As masters of genome-wide regulation, miRNAs represent a key component in the complex architecture of cellular processes. Over the last decade, it has become increasingly apparent that miRNAs have many important roles in the development of disease and cancer.
Sara-Elizabeth, Cardin, Glen M, Borchert
openaire   +2 more sources

MicroRNA Expression: Protein Participants in MicroRNA Regulation

2017
MiRNAs are ~20 nt small RNAs that regulate networks of proteins using a seed region of nucleotides 2-8 to complement the 3' UTR of target mRNAs. The biogenesis and function of miRNAs as translational repressors is facilitated by protein counterparts that process primary and precursor miRNAs to maturity (Drosha/DCGR8 and Dicer/TRBP respectively) and ...
Valeria M, King, Glen M, Borchert
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MicroRNA biogenesis: coordinated cropping and dicing

Nature Reviews Molecular Cell Biology, 2005
Vic Narry Kim
exaly  

microRNA, epi-microRNA, and cancer

2023
Michaela B. Kirschner, Harriet R. Walker, Hannah L. Moody   +2 more
openaire   +1 more source

MicroRNA control of signal transduction

Nature Reviews Molecular Cell Biology, 2010
Masafumi Inui, Graziano Martello
exaly