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Therapeutic potential of synthetic microRNA mimics based on the miR-15/107 consensus sequence. [PDF]

open access: yesCancer Gene Ther
Reid G   +11 more
europepmc   +1 more source
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MicroRNAs Regulating MicroRNAs in Cancer

Trends in Cancer, 2018
MicroRNAs (miRNA) are capable of self-regulation, termed miRNA to miRNA interaction. Very little is known about these interactions and their impact on the cellular milieu. We discuss known miRNA to miRNA interactions, potential mechanisms, and their role in cancer.
Meredith Hill, Nham Tran, Nham Tran
openaire   +2 more sources

MicroRNAs

The Cancer Journal, 2008
MicroRNAs (miRNAs) are small, noncoding RNAs with regulatory functions, which play an important role in many human diseases, including cancer. An emerging number of studies show that miRNAs can act either as oncogenes or as tumor suppressor genes or sometimes as both. Germline, somatic mutations and polymorphisms can contribute to cancer predisposition.
Muller, Fabbri   +2 more
openaire   +2 more sources

The MicroRNA

2012
MicroRNAs (miRNAs), widely distributed, small regulatory RNA genes, target both messenger RNA (mRNA) degradation and suppression of protein translation based on sequence complementarity between the miRNA and its targeted mRNA. Different names have been used to describe various types of miRNA. During evolution, RNA retroviruses or transgenes invaded the
Shao-Yao, Ying   +2 more
openaire   +3 more sources

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