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This is the second installment in the series, “The Interview with the World‐Class Authorities.” We are honored to welcome Prof. Luis Diaz, the Director of the Division of Solid Tumor Oncology at Memorial Sloan Kettering Cancer Center and Editor‐in‐Chief of Cancer Discovery. Prof.
Haruna Takeda+4 more
wiley +1 more source
Microsatellite Instability, Epstein-Barr Virus, p53, and β-Catenin in Early Gastric Cancers: Clinicopathologic Association. [PDF]
Kim J, Choi J, Kwon HJ, Kim M.
europepmc +1 more source
Development and Characterization of the NISTCHO Reference Cell Line
Graphical Abstract and Lay Summary We report the development and characterization of a new reference cell line, which is a Chinese hamster ovary cell line host expressing a nonoriginator version of RM 8671 NISTmAb. This reference cell line was selected due to its suitable growth and productivity, product quality, and transgene integration profile.
Hussain Dahodwala+19 more
wiley +1 more source
Application of immune checkpoint inhibitors and microsatellite instability in gastric cancer. [PDF]
Yan SY, Fan JG.
europepmc +1 more source
ABSTRACT Background T‐cell receptor (TCR) diversity 50 (D50) values could assess peripheral blood (PB) TCR diversity and immunity. This study aimed to evaluate the potential D50 value in the diagnosis and treatment evaluation of colorectal cancer (CRC) and nonsmall‐cell lung cancer (NSCLC). Methods This prospective observational study enrolled patients
Jilong Ma+7 more
wiley +1 more source
Potential value of novel multiparametric MRI radiomics for preoperative prediction of microsatellite instability and Ki-67 expression in endometrial cancer. [PDF]
Wang Z+8 more
europepmc +1 more source
Advances in the Study of Metabolic Reprogramming in Gastric Cancer
ABSTRACT Background Gastric cancer is one of the most prevalent malignancies of the digestive system and is associated with a poor prognosis, particularly in advanced metastatic stages, where the 5‐year survival rate is significantly low. Methods Recent research has demonstrated that metabolic reprogramming—including alterations in glucose, lipid, and ...
Yu Rong, Yuanyin Teng, Xiaoying Zhou
wiley +1 more source
Which occurs first, ARID1A inactivation or microsatellite instability?: A comment to Yamamoto et al. (2024). [PDF]
Lee D.
europepmc +1 more source
Centromere Protein F in Tumor Biology: Cancer's Achilles Heel
ABSTRACT Background Centromere protein F (CENP‐F) is an important nuclear matrix protein that regulates mitosis and the cell cycle, and plays a crucial role in recruiting spindle checkpoint proteins to maintain the accuracy of chromosome segregation.
Zitong Wan+11 more
wiley +1 more source